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Severe toxicity to capecitabine due to a new variant at a donor splicing site in the dihydropyrimidine dehydrogenase (DPYD) gene.
García-González X, López-Tarruella S, García MI, González-Haba E, Blanco C, Salvador-Martin S, Jerez Y, Thomas F, Jarama M, Sáez MS, Martín M, López-Fernández LA. García-González X, et al. Cancer Manag Res. 2018 Oct 11;10:4517-4522. doi: 10.2147/CMAR.S174470. eCollection 2018. Cancer Manag Res. 2018. PMID: 30349384 Free PMC article.
Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.
Salvador-Martín S, García-González X, García MI, Blanco C, García-Alfonso P, Robles L, Grávalos C, Pachón V, Longo F, Martínez V, Sanjurjo-Sáez M, López-Fernández LA. Salvador-Martín S, et al. Pharmacol Res. 2018 Oct;136:133-139. doi: 10.1016/j.phrs.2018.08.026. Epub 2018 Sep 11. Pharmacol Res. 2018. PMID: 30213564
New DPYD variants causing DPD deficiency in patients treated with fluoropyrimidine.
García-González X, Kaczmarczyk B, Abarca-Zabalía J, Thomas F, García-Alfonso P, Robles L, Pachón V, Vaz Á, Salvador-Martín S, Sanjurjo-Sáez M, López-Fernández LA. García-González X, et al. Cancer Chemother Pharmacol. 2020 Jul;86(1):45-54. doi: 10.1007/s00280-020-04093-1. Epub 2020 Jun 11. Cancer Chemother Pharmacol. 2020. PMID: 32529295
DPYD Exome, mRNA Expression and Uracil Levels in Early Severe Toxicity to Fluoropyrimidines: An Extreme Phenotype Approach.
Villalvazo P, Marzal-Alfaro B, García-Alfonso P, Revuelta-Herrero JL, Thomas F, López-Tarruella S, García-González X, Calvo A, Yakoubi M, Salvador-Martín S, López-López F, Aguilar I, Sanjurjo-Sáez M, Martín M, López-Fernández LA. Villalvazo P, et al. J Pers Med. 2021 Aug 13;11(8):792. doi: 10.3390/jpm11080792. J Pers Med. 2021. PMID: 34442436 Free PMC article.
Genetic predictors of long-term response and trough levels of infliximab in crohn's disease.
Salvador-Martín S, López-Cauce B, Nuñez O, Laserna-Mendieta EJ, García MI, Lobato E, Abarca-Zabalía J, Sanjurjo-Saez M, Lucendo AJ, Marín-Jiménez I, Menchén LA, López-Fernández LA. Salvador-Martín S, et al. Pharmacol Res. 2019 Nov;149:104478. doi: 10.1016/j.phrs.2019.104478. Epub 2019 Oct 9. Pharmacol Res. 2019. PMID: 31605784
Genetic Predictors of Long-term Response to Antitumor Necrosis Factor Agents in Pediatric Inflammatory Bowel Disease.
Salvador-Martín S, Bossacoma F, Pujol-Muncunill G, Navas-López VM, Gallego-Fernández C, Viada J, Muñoz-Codoceo R, Magallares L, Martínez-Ojinaga E, Moreno-Álvarez A, Solar-Boga A, Segarra O, Clemente S, Rodriguez-Martinez A, Alvarez-Vayo C, Loverdos I, Merino-Bohórquez V, Balboa-Vega MJ, Blanca-García JA, Fobelo MJ, Millán-Jiménez A, García-Romero R, Sanchez C, Tolín M, Caldas RG, Eizaguirre FJ, Sánchez-Hernandez JG, Torres-Peral R, Aznal E, García-González X, Sanjurjo-Sáez M, López-Fernández LA. Salvador-Martín S, et al. J Pediatr Gastroenterol Nutr. 2020 Oct;71(4):508-515. doi: 10.1097/MPG.0000000000002840. J Pediatr Gastroenterol Nutr. 2020. PMID: 32773718
22 results