Wang C - Search Results

1

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.

Zhang CJ, Jiang M, Zhou H, Liu W, Wang C, Kang Z, Han B, Zhang Q, Chen X, Xiao J, Fisher A, Kaiser WJ, Murayama MA, Iwakura Y, Gao J, Carman J, Dongre A, Dubyak G, Abbott DW, Shi FD, Ransohoff RM, Li X. Zhang CJ, et al. Among authors: wang c. J Clin Invest. 2018 Dec 3;128(12):5399-5412. doi: 10.1172/JCI121901. Epub 2018 Oct 29. J Clin Invest. 2018. PMID: 30372424 Free PMC article.

2

A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.

Liu C, Swaidani S, Qian W, Kang Z, Sun P, Han Y, Wang C, Gulen MF, Yin W, Zhang C, Fox PL, Aronica M, Hamilton TA, Misra S, Deng J, Li X. Liu C, et al. Among authors: wang c. Sci Signal. 2011 Nov 1;4(197):ra72. doi: 10.1126/scisignal.2001843. Sci Signal. 2011. PMID: 22045852 Free PMC article.

3

Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.

Kang Z, Swaidani S, Yin W, Wang C, Barlow JL, Gulen MF, Bulek K, Do JS, Aronica M, McKenzie AN, Min B, Li X. Kang Z, et al. Among authors: wang c. Immunity. 2012 May 25;36(5):821-33. doi: 10.1016/j.immuni.2012.03.021. Epub 2012 May 17. Immunity. 2012. PMID: 22608496 Free PMC article.

4

IL-17-induced Act1-mediated signaling is critical for cuprizone-induced demyelination.

Kang Z, Liu L, Spangler R, Spear C, Wang C, Gulen MF, Veenstra M, Ouyang W, Ransohoff RM, Li X. Kang Z, et al. Among authors: wang c. J Neurosci. 2012 Jun 13;32(24):8284-92. doi: 10.1523/JNEUROSCI.0841-12.2012. J Neurosci. 2012. PMID: 22699909 Free PMC article.

5

The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.

Wang C, Wu L, Bulek K, Martin BN, Zepp JA, Kang Z, Liu C, Herjan T, Misra S, Carman JA, Gao J, Dongre A, Han S, Bunting KD, Ko JS, Xiao H, Kuchroo VK, Ouyang W, Li X. Wang C, et al. Nat Immunol. 2013 Jan;14(1):72-81. doi: 10.1038/ni.2479. Epub 2012 Dec 2. Nat Immunol. 2013. PMID: 23202271 Free PMC article.

6

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells.

Kang Z, Wang C, Zepp J, Wu L, Sun K, Zhao J, Chandrasekharan U, DiCorleto PE, Trapp BD, Ransohoff RM, Li X. Kang Z, et al. Among authors: wang c. Nat Neurosci. 2013 Oct;16(10):1401-8. doi: 10.1038/nn.3505. Epub 2013 Sep 1. Nat Neurosci. 2013. PMID: 23995070 Free PMC article.

7

IKKα negatively regulates ASC-dependent inflammasome activation.

Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, Karin M, Nuñez G, Dubyak G, Hu Y, Li X. Martin BN, et al. Among authors: wang c. Nat Commun. 2014 Sep 30;5:4977. doi: 10.1038/ncomms5977. Nat Commun. 2014. PMID: 25266676 Free PMC article.

8

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.

Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X. Martin BN, et al. Among authors: wang c. Nat Immunol. 2016 May;17(5):583-92. doi: 10.1038/ni.3389. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998763 Free PMC article.

9

The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo.

Liu C, Zhu L, Fukuda K, Ouyang S, Chen X, Wang C, Zhang CJ, Martin B, Gu C, Qin L, Rachakonda S, Aronica M, Qin J, Li X. Liu C, et al. Among authors: wang c. Sci Signal. 2017 Feb 21;10(467):eaaf8823. doi: 10.1126/scisignal.aaf8823. Sci Signal. 2017. PMID: 28223414 Free PMC article.

10

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression.

Wang C, Zhang CJ, Martin BN, Bulek K, Kang Z, Zhao J, Bian G, Carman JA, Gao J, Dongre A, Xue H, Miller SD, Qian Y, Hambardzumyan D, Hamilton T, Ransohoff RM, Li X. Wang C, et al. Nat Commun. 2017 May 31;8:15508. doi: 10.1038/ncomms15508. Nat Commun. 2017. PMID: 28561022 Free PMC article.

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