Nestorov I - Search Results

1

A pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans.

Biliouris K, Nestorov I, Naik H, Dai D, Xiao G, Wang Q, Pellerin A, Rabah D, Lesko LJ, Trame MN. Biliouris K, et al. Among authors: nestorov i. J Pharmacokinet Pharmacodyn. 2018 Dec;45(6):817-827. doi: 10.1007/s10928-018-9609-6. Epub 2018 Oct 30. J Pharmacokinet Pharmacodyn. 2018. PMID: 30377889

2

A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.

Biliouris K, Gaitonde P, Yin W, Norris DA, Wang Y, Henry S, Fey R, Nestorov I, Schmidt S, Rogge M, Lesko LJ, Trame MN. Biliouris K, et al. Among authors: nestorov i. CPT Pharmacometrics Syst Pharmacol. 2018 Sep;7(9):581-592. doi: 10.1002/psp4.12323. Epub 2018 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30043511 Free PMC article.

3

A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus.

Hartmann S, Biliouris K, Naik H, Rabah D, Stevenson L, Shen C, Nestorov IA, Lesko LJ, Trame MN. Hartmann S, et al. J Pharmacokinet Pharmacodyn. 2020 Jun;47(3):255-266. doi: 10.1007/s10928-020-09688-y. Epub 2020 Apr 25. J Pharmacokinet Pharmacodyn. 2020. PMID: 32335844 Clinical Trial.

4

Exposure-disease response analysis of natalizumab in subjects with multiple sclerosis.

Muralidharan KK, Steiner D, Amarante D, Ho PR, Mikol D, Elkins J, Subramanyam M, Nestorov I. Muralidharan KK, et al. Among authors: nestorov i. J Pharmacokinet Pharmacodyn. 2017 Jun;44(3):263-275. doi: 10.1007/s10928-017-9514-4. Epub 2017 Mar 1. J Pharmacokinet Pharmacodyn. 2017. PMID: 28251386

5

Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration.

Wang Q, Delva L, Weinreb PH, Pepinsky RB, Graham D, Veizaj E, Cheung AE, Chen W, Nestorov I, Rohde E, Caputo R, Kuesters GM, Bohnert T, Gan LS. Wang Q, et al. Among authors: nestorov i. Fluids Barriers CNS. 2018 Mar 20;15(1):10. doi: 10.1186/s12987-018-0093-6. Fluids Barriers CNS. 2018. PMID: 29558954 Free PMC article.

6

Analysis of peginterferon β-1a exposure and Gd-enhanced lesion or T2 lesion response in relapsing-remitting multiple sclerosis patients.

Hang Y, Hu X, Zhang J, Liu S, Deykin A, Nestorov I. Hang Y, et al. Among authors: nestorov i. J Pharmacokinet Pharmacodyn. 2016 Aug;43(4):371-83. doi: 10.1007/s10928-016-9477-x. Epub 2016 Jun 14. J Pharmacokinet Pharmacodyn. 2016. PMID: 27299457 Free PMC article. Clinical Trial.

7

A physiologically-based pharmacokinetic model to describe antisense oligonucleotide distribution after intrathecal administration.

Monine M, Norris D, Wang Y, Nestorov I. Monine M, et al. Among authors: nestorov i. J Pharmacokinet Pharmacodyn. 2021 Oct;48(5):639-654. doi: 10.1007/s10928-021-09761-0. Epub 2021 May 15. J Pharmacokinet Pharmacodyn. 2021. PMID: 33991294

8

Population Pharmacokinetics of Daclizumab High-Yield Process in Healthy Volunteers and Subjects with Multiple Sclerosis: Analysis of Phase I-III Clinical Trials.

Diao L, Hang Y, Othman AA, Nestorov I, Tran JQ. Diao L, et al. Among authors: nestorov i. Clin Pharmacokinet. 2016 Aug;55(8):943-55. doi: 10.1007/s40262-016-0366-7. Clin Pharmacokinet. 2016. PMID: 26873229 Clinical Trial.

9

Population pharmacokinetic modeling of subcutaneously administered etanercept in patients with psoriasis.

Nestorov I, Zitnik R, Ludden T. Nestorov I, et al. J Pharmacokinet Pharmacodyn. 2004 Dec;31(6):463-90. doi: 10.1007/s10928-005-5912-0. J Pharmacokinet Pharmacodyn. 2004. PMID: 16222785

10

Population pharmacokinetic modelling of recombinant factor IX Fc fusion protein (rFIXFc) in patients with haemophilia B.

Diao L, Li S, Ludden T, Gobburu J, Nestorov I, Jiang H. Diao L, et al. Among authors: nestorov i. Clin Pharmacokinet. 2014 May;53(5):467-77. doi: 10.1007/s40262-013-0129-7. Clin Pharmacokinet. 2014. PMID: 24452809 Free PMC article. Clinical Trial.

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