Klenerman D - Search Results

1

Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale.

Lee JE, Sang JC, Rodrigues M, Carr AR, Horrocks MH, De S, Bongiovanni MN, Flagmeier P, Dobson CM, Wales DJ, Lee SF, Klenerman D. Lee JE, et al. Among authors: klenerman d. Nano Lett. 2018 Dec 12;18(12):7494-7501. doi: 10.1021/acs.nanolett.8b02916. Epub 2018 Nov 7. Nano Lett. 2018. PMID: 30380895 Free PMC article.

2

Nanoscale pipetting for controlled chemistry in small arrayed water droplets using a double-barrel pipet.

Rodolfa KT, Bruckbauer A, Zhou D, Schevchuk AI, Korchev YE, Klenerman D. Rodolfa KT, et al. Among authors: klenerman d. Nano Lett. 2006 Feb;6(2):252-7. doi: 10.1021/nl052215i. Nano Lett. 2006. PMID: 16464045

3

Macroscopic 2D networks self-assembled from nanometer-sized protein/DNA complexes.

Manzanera M, Frankel DJ, Li H, Zhou D, Bruckbauer A, Kreutzmann P, Blackburn JM, Abell C, Rayment T, Klenerman D, Barker PD. Manzanera M, et al. Among authors: klenerman d. Nano Lett. 2006 Mar;6(3):365-70. doi: 10.1021/nl051599+. Nano Lett. 2006. PMID: 16522024

4

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence.

Orte A, Birkett NR, Clarke RW, Devlin GL, Dobson CM, Klenerman D. Orte A, et al. Among authors: klenerman d. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14424-9. doi: 10.1073/pnas.0803086105. Epub 2008 Sep 16. Proc Natl Acad Sci U S A. 2008. PMID: 18796612 Free PMC article.

5

Single molecule fluorescence under conditions of fast flow.

Horrocks MH, Li H, Shim JU, Ranasinghe RT, Clarke RW, Huck WT, Abell C, Klenerman D. Horrocks MH, et al. Among authors: klenerman d. Anal Chem. 2012 Jan 3;84(1):179-85. doi: 10.1021/ac202313d. Epub 2011 Dec 6. Anal Chem. 2012. PMID: 22147688

6

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide.

Narayan P, Orte A, Clarke RW, Bolognesi B, Hook S, Ganzinger KA, Meehan S, Wilson MR, Dobson CM, Klenerman D. Narayan P, et al. Among authors: klenerman d. Nat Struct Mol Biol. 2011 Dec 18;19(1):79-83. doi: 10.1038/nsmb.2191. Nat Struct Mol Biol. 2011. PMID: 22179788 Free PMC article.

7

Direct observation of the interconversion of normal and toxic forms of α-synuclein.

Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D. Cremades N, et al. Among authors: klenerman d. Cell. 2012 May 25;149(5):1048-59. doi: 10.1016/j.cell.2012.03.037. Cell. 2012. PMID: 22632969 Free PMC article.

8

Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones.

Narayan P, Meehan S, Carver JA, Wilson MR, Dobson CM, Klenerman D. Narayan P, et al. Among authors: klenerman d. Biochemistry. 2012 Nov 20;51(46):9270-6. doi: 10.1021/bi301277k. Epub 2012 Nov 8. Biochemistry. 2012. PMID: 23106396 Free PMC article.

9

Ubiquitin chain conformation regulates recognition and activity of interacting proteins.

Ye Y, Blaser G, Horrocks MH, Ruedas-Rama MJ, Ibrahim S, Zhukov AA, Orte A, Klenerman D, Jackson SE, Komander D. Ye Y, et al. Among authors: klenerman d. Nature. 2012 Dec 13;492(7428):266-70. doi: 10.1038/nature11722. Epub 2012 Dec 2. Nature. 2012. PMID: 23201676 Free PMC article.

10

Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells.

Narayan P, Ganzinger KA, McColl J, Weimann L, Meehan S, Qamar S, Carver JA, Wilson MR, St George-Hyslop P, Dobson CM, Klenerman D. Narayan P, et al. Among authors: klenerman d. J Am Chem Soc. 2013 Jan 30;135(4):1491-8. doi: 10.1021/ja3103567. Epub 2013 Jan 22. J Am Chem Soc. 2013. PMID: 23339742 Free PMC article.

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