Karn J - Search Results

1

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA.

Chen L, Feng Z, Yue H, Bazdar D, Mbonye U, Zender C, Harding CV, Bruggeman L, Karn J, Sieg SF, Wang B, Jin G. Chen L, et al. Among authors: karn j. Nat Commun. 2018 Nov 2;9(1):4585. doi: 10.1038/s41467-018-07006-2. Nat Commun. 2018. PMID: 30389917 Free PMC article.

2

Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA.

Lalonde MS, Lobritz MA, Ratcliff A, Chamanian M, Athanassiou Z, Tyagi M, Wong J, Robinson JA, Karn J, Varani G, Arts EJ. Lalonde MS, et al. Among authors: karn j. PLoS Pathog. 2011 May;7(5):e1002038. doi: 10.1371/journal.ppat.1002038. Epub 2011 May 19. PLoS Pathog. 2011. PMID: 21625572 Free PMC article.

3

T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway.

Kim YK, Mbonye U, Hokello J, Karn J. Kim YK, et al. Among authors: karn j. J Mol Biol. 2011 Jul 29;410(5):896-916. doi: 10.1016/j.jmb.2011.03.054. J Mol Biol. 2011. PMID: 21763495 Free PMC article.

4

Control of HIV latency by epigenetic and non-epigenetic mechanisms.

Mbonye U, Karn J. Mbonye U, et al. Among authors: karn j. Curr HIV Res. 2011 Dec 1;9(8):554-67. doi: 10.2174/157016211798998736. Curr HIV Res. 2011. PMID: 22211660 Free PMC article.

5

Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.

Mbonye UR, Gokulrangan G, Datt M, Dobrowolski C, Cooper M, Chance MR, Karn J. Mbonye UR, et al. Among authors: karn j. PLoS Pathog. 2013;9(5):e1003338. doi: 10.1371/journal.ppat.1003338. Epub 2013 May 2. PLoS Pathog. 2013. PMID: 23658523 Free PMC article. Clinical Trial.

6

Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication.

Yu X, Shahir AM, Sha J, Feng Z, Eapen B, Nithianantham S, Das B, Karn J, Weinberg A, Bissada NF, Ye F. Yu X, et al. Among authors: karn j. J Virol. 2014 Apr;88(8):4466-79. doi: 10.1128/JVI.03326-13. Epub 2014 Feb 5. J Virol. 2014. PMID: 24501407 Free PMC article.

7

Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure.

Mbonye U, Karn J. Mbonye U, et al. Among authors: karn j. Virology. 2014 Apr;454-455:328-39. doi: 10.1016/j.virol.2014.02.008. Epub 2014 Feb 22. Virology. 2014. PMID: 24565118 Free PMC article. Review.

8

Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.

Jadlowsky JK, Wong JY, Graham AC, Dobrowolski C, Devor RL, Adams MD, Fujinaga K, Karn J. Jadlowsky JK, et al. Among authors: karn j. Mol Cell Biol. 2014 Jun;34(11):1911-28. doi: 10.1128/MCB.01013-13. Epub 2014 Mar 17. Mol Cell Biol. 2014. PMID: 24636995 Free PMC article.

9

The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events.

Lucera MB, Tilton CA, Mao H, Dobrowolski C, Tabler CO, Haqqani AA, Karn J, Tilton JC. Lucera MB, et al. Among authors: karn j. J Virol. 2014 Sep;88(18):10803-12. doi: 10.1128/JVI.00320-14. Epub 2014 Jul 9. J Virol. 2014. PMID: 25008921 Free PMC article.

10

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection.

Hu W, Kaminski R, Yang F, Zhang Y, Cosentino L, Li F, Luo B, Alvarez-Carbonell D, Garcia-Mesa Y, Karn J, Mo X, Khalili K. Hu W, et al. Among authors: karn j. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11461-6. doi: 10.1073/pnas.1405186111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049410 Free PMC article.

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