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Hit-to-Lead: Hit Validation and Assessment.
Hevener KE, Pesavento R, Ren J, Lee H, Ratia K, Johnson ME. Hevener KE, et al. Among authors: ren j. Methods Enzymol. 2018;610:265-309. doi: 10.1016/bs.mie.2018.09.022. Epub 2018 Oct 25. Methods Enzymol. 2018. PMID: 30390802
High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads.
Wolf NM, Lee H, Choules MP, Pauli GF, Phansalkar R, Anderson JR, Gao W, Ren J, Santarsiero BD, Lee H, Cheng J, Jin YY, Ho NA, Duc NM, Suh JW, Abad-Zapatero C, Cho S. Wolf NM, et al. Among authors: ren j. ACS Infect Dis. 2019 Jun 14;5(6):829-840. doi: 10.1021/acsinfecdis.8b00276. Epub 2019 May 3. ACS Infect Dis. 2019. PMID: 30990022 Free PMC article.
Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of vraTSR Expression in Methicillin-Resistant Staphylococcus aureus.
Lee H, Boyle-Vavra S, Ren J, Jarusiewicz JA, Sharma LK, Hoagland DT, Yin S, Zhu T, Hevener KE, Ojeda I, Lee RE, Daum RS, Johnson ME. Lee H, et al. Among authors: ren j. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e02593-18. doi: 10.1128/AAC.02593-18. Print 2019 Sep. Antimicrob Agents Chemother. 2019. PMID: 31209003 Free PMC article.
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