Cheng X - Search Results

1

Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.

Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall MD, Simeonov A, Fu H, Vertino PM, Cheng X. Horton JR, et al. Among authors: cheng x. J Med Chem. 2018 Dec 13;61(23):10588-10601. doi: 10.1021/acs.jmedchem.8b01219. Epub 2018 Nov 15. J Med Chem. 2018. PMID: 30392349 Free PMC article.

2

Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p.

Green DM, Marfatia KA, Crafton EB, Zhang X, Cheng X, Corbett AH. Green DM, et al. Among authors: cheng x. J Biol Chem. 2002 Mar 8;277(10):7752-60. doi: 10.1074/jbc.M110053200. Epub 2002 Jan 4. J Biol Chem. 2002. PMID: 11779864 Free article.

3

The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.

Qiu C, Sawada K, Zhang X, Cheng X. Qiu C, et al. Among authors: cheng x. Nat Struct Biol. 2002 Mar;9(3):217-24. doi: 10.1038/nsb759. Nat Struct Biol. 2002. PMID: 11836534 Free PMC article.

4

Determinants of the interaction of the spinal muscular atrophy disease protein SMN with the dimethylarginine-modified box H/ACA small nucleolar ribonucleoprotein GAR1.

Whitehead SE, Jones KW, Zhang X, Cheng X, Terns RM, Terns MP. Whitehead SE, et al. Among authors: cheng x. J Biol Chem. 2002 Dec 13;277(50):48087-93. doi: 10.1074/jbc.M204551200. Epub 2002 Sep 19. J Biol Chem. 2002. PMID: 12244096 Free article.

5

Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase.

Zhang X, Tamaru H, Khan SI, Horton JR, Keefe LJ, Selker EU, Cheng X. Zhang X, et al. Among authors: cheng x. Cell. 2002 Oct 4;111(1):117-27. doi: 10.1016/s0092-8674(02)00999-6. Cell. 2002. PMID: 12372305 Free PMC article.

6

Structure of the SET domain histone lysine methyltransferase Clr4.

Min J, Zhang X, Cheng X, Grewal SI, Xu RM. Min J, et al. Among authors: cheng x. Nat Struct Biol. 2002 Nov;9(11):828-32. doi: 10.1038/nsb860. Nat Struct Biol. 2002. PMID: 12389037

7

Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4.

Wu P, Qiu C, Sohail A, Zhang X, Bhagwat AS, Cheng X. Wu P, et al. Among authors: cheng x. J Biol Chem. 2003 Feb 14;278(7):5285-91. doi: 10.1074/jbc.M210884200. Epub 2002 Nov 26. J Biol Chem. 2003. PMID: 12456671 Free PMC article.

8

Structure of the predominant protein arginine methyltransferase PRMT1 and analysis of its binding to substrate peptides.

Zhang X, Cheng X. Zhang X, et al. Among authors: cheng x. Structure. 2003 May;11(5):509-20. doi: 10.1016/s0969-2126(03)00071-6. Structure. 2003. PMID: 12737817 Free PMC article.

9

Structural basis for the product specificity of histone lysine methyltransferases.

Zhang X, Yang Z, Khan SI, Horton JR, Tamaru H, Selker EU, Cheng X. Zhang X, et al. Among authors: cheng x. Mol Cell. 2003 Jul;12(1):177-85. doi: 10.1016/s1097-2765(03)00224-7. Mol Cell. 2003. PMID: 12887903 Free PMC article.

10

Structure of the bacteriophage T4 DNA adenine methyltransferase.

Yang Z, Horton JR, Zhou L, Zhang XJ, Dong A, Zhang X, Schlagman SL, Kossykh V, Hattman S, Cheng X. Yang Z, et al. Among authors: cheng x. Nat Struct Biol. 2003 Oct;10(10):849-55. doi: 10.1038/nsb973. Epub 2003 Aug 24. Nat Struct Biol. 2003. PMID: 12937411 Free PMC article.

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