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Page 1
Congenital defects in neutrophil dynamics.
Keszei M, Westerberg LS. Keszei M, et al. J Immunol Res. 2014;2014:303782. doi: 10.1155/2014/303782. Epub 2014 Aug 5. J Immunol Res. 2014. PMID: 25165726 Free PMC article. Review.
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.
Baptista MA, Keszei M, Oliveira M, Sunahara KK, Andersson J, Dahlberg CI, Worth AJ, Liedén A, Kuo IC, Wallin RP, Snapper SB, Eidsmo L, Scheynius A, Karlsson MC, Bouma G, Burns SO, Forsell MN, Thrasher AJ, Nylén S, Westerberg LS. Baptista MA, et al. Among authors: keszei m. Nat Commun. 2016 Jul 18;7:12175. doi: 10.1038/ncomms12175. Nat Commun. 2016. PMID: 27425374 Free PMC article.
Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive.
Keszei M, Record J, Kritikou JS, Wurzer H, Geyer C, Thiemann M, Drescher P, Brauner H, Köcher L, James J, He M, Baptista MA, Dahlberg CI, Biswas A, Lane DP, Song W, Pütsep K, Vandenberghe P, Snapper SB, Westerberg LS. Keszei M, et al. J Clin Invest. 2018 Aug 31;128(9):4115-4131. doi: 10.1172/JCI64772. Epub 2018 Aug 20. J Clin Invest. 2018. PMID: 30124469 Free PMC article.
Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells.
Kritikou JS, Oliveira MM, Record J, Saeed MB, Nigam SM, He M, Keszei M, Wagner AK, Brauner H, Sendel A, Sedimbi SK, Rentouli S, Lane DP, Snapper SB, Kärre K, Vandenberghe P, Orange JS, Westerberg LS. Kritikou JS, et al. Among authors: keszei m. JCI Insight. 2021 Mar 22;6(6):e140273. doi: 10.1172/jci.insight.140273. JCI Insight. 2021. PMID: 33621210 Free PMC article.
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.
He M, Saeed MB, Record J, Keszei M, Gonçalves Pinho L, Vasconcelos-Fontes L, D'Aulerio R, Vieira R, Oliveira MMS, Geyer C, Bohaumilitzky L, Thiemann M, Deordieva E, Buedts L, Matias Lopes JP, Pershin D, Hammarström L, Xia Y, Zhao X, Cunningham-Rundles C, Thrasher AJ, Burns SO, Cotta-de-Almeida V, Liu C, Shcherbina A, Vandenberghe P, Westerberg LS. He M, et al. Among authors: keszei m. J Allergy Clin Immunol. 2022 Mar;149(3):1069-1084. doi: 10.1016/j.jaci.2021.07.033. Epub 2021 Aug 9. J Allergy Clin Immunol. 2022. PMID: 34384840 Free article.
A gain-of-function variant in the Wiskott-Aldrich syndrome gene is associated with a MYH9-related disease-like syndrome.
Marx D, Dupuis A, Eckly A, Molitor A, Olagne J, Touchard G, Kaaki S, Ory C, Faller AL, Gérard B, Cotter M, Westerberg L, Keszei M, Moulin B, Gachet C, Caillard S, Bahram S, Carapito R. Marx D, et al. Among authors: keszei m. Blood Adv. 2022 Sep 27;6(18):5279-5284. doi: 10.1182/bloodadvances.2021006789. Blood Adv. 2022. PMID: 35404999 Free PMC article.
Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells.
Madapura HS, Nagy N, Ujvari D, Kallas T, Kröhnke MCL, Amu S, Björkholm M, Stenke L, Mandal PK, McMurray JS, Keszei M, Westerberg LS, Cheng H, Xue F, Klein G, Klein E, Salamon D. Madapura HS, et al. Among authors: keszei m. Oncogene. 2017 Aug 10;36(32):4619-4628. doi: 10.1038/onc.2017.85. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368400
45 results