Spires-Jones T - Search Results

1

Invited Review: APOE at the interface of inflammation, neurodegeneration and pathological protein spread in Alzheimer's disease.

Tzioras M, Davies C, Newman A, Jackson R, Spires-Jones T. Tzioras M, et al. Neuropathol Appl Neurobiol. 2019 Jun;45(4):327-346. doi: 10.1111/nan.12529. Epub 2018 Nov 28. Neuropathol Appl Neurobiol. 2019. PMID: 30394574 Free PMC article. Review.

2

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model.

Spires-Jones TL, Meyer-Luehmann M, Osetek JD, Jones PB, Stern EA, Bacskai BJ, Hyman BT. Spires-Jones TL, et al. Am J Pathol. 2007 Oct;171(4):1304-11. doi: 10.2353/ajpath.2007.070055. Epub 2007 Aug 23. Am J Pathol. 2007. PMID: 17717139 Free PMC article.

3

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease.

Spires-Jones TL, Mielke ML, Rozkalne A, Meyer-Luehmann M, de Calignon A, Bacskai BJ, Schenk D, Hyman BT. Spires-Jones TL, et al. Neurobiol Dis. 2009 Feb;33(2):213-20. doi: 10.1016/j.nbd.2008.10.011. Epub 2008 Nov 6. Neurobiol Dis. 2009. PMID: 19028582 Free PMC article.

4

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques.

Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M, Micheva KD, Smith SJ, Kim ML, Lee VM, Hyman BT, Spires-Jones TL. Koffie RM, et al. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4012-7. doi: 10.1073/pnas.0811698106. Epub 2009 Feb 19. Proc Natl Acad Sci U S A. 2009. PMID: 19228947 Free PMC article.

5

A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model.

Rozkalne A, Spires-Jones TL, Stern EA, Hyman BT. Rozkalne A, et al. Brain Res. 2009 Jul 14;1280:178-85. doi: 10.1016/j.brainres.2009.05.045. Epub 2009 May 22. Brain Res. 2009. PMID: 19465012 Free PMC article.

6

Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy.

de Calignon A, Spires-Jones TL, Pitstick R, Carlson GA, Hyman BT. de Calignon A, et al. J Neuropathol Exp Neurol. 2009 Jul;68(7):757-61. doi: 10.1097/NEN.0b013e3181a9fc66. J Neuropathol Exp Neurol. 2009. PMID: 19535996 Free PMC article.

7

Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice.

Rozkalne A, Hyman BT, Spires-Jones TL. Rozkalne A, et al. Neurobiol Dis. 2011 Mar;41(3):650-4. doi: 10.1016/j.nbd.2010.11.014. Epub 2010 Dec 4. Neurobiol Dis. 2011. PMID: 21134458 Free PMC article.

8

Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging.

Spires-Jones TL, de Calignon A, Meyer-Luehmann M, Bacskai BJ, Hyman BT. Spires-Jones TL, et al. Methods. 2011 Mar;53(3):201-7. doi: 10.1016/j.ymeth.2010.12.009. Epub 2010 Dec 14. Methods. 2011. PMID: 21163350 Free PMC article.

9

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain.

Jones PB, Adams KW, Rozkalne A, Spires-Jones TL, Hshieh TT, Hashimoto T, von Armin CA, Mielke M, Bacskai BJ, Hyman BT. Jones PB, et al. PLoS One. 2011 Jan 31;6(1):e14586. doi: 10.1371/journal.pone.0014586. PLoS One. 2011. PMID: 21297948 Free PMC article.

10

Are tangles as toxic as they look?

Spires-Jones TL, Kopeikina KJ, Koffie RM, de Calignon A, Hyman BT. Spires-Jones TL, et al. J Mol Neurosci. 2011 Nov;45(3):438-44. doi: 10.1007/s12031-011-9566-7. Epub 2011 Jun 3. J Mol Neurosci. 2011. PMID: 21638071 Free PMC article. Review.

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