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Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma.
Aly AA, El-Sheref EM, Bakheet MEM, Mourad MAE, Bräse S, Ibrahim MAA, Nieger M, Garvalov BK, Dalby KN, Kaoud TS. Aly AA, et al. Among authors: dalby kn. Bioorg Chem. 2019 Feb;82:290-305. doi: 10.1016/j.bioorg.2018.10.044. Epub 2018 Oct 23. Bioorg Chem. 2019. PMID: 30396063 Free PMC article.
Maternal Embryonic Leucine Zipper Kinase is Associated with Metastasis in Triple-negative Breast Cancer.
Xie X, Chauhan GB, Edupuganti R, Kogawa T, Park J, Tacam M, Tan AW, Mughees M, Vidhu F, Liu DD, Taliaferro JM, Pitner MK, Browning LS, Lee JH, Shen Y, Wang J, Ueno NT, Krishnamurthy S, Hortobagyi GN, Tripathy D, Van Laere SJ, Bartholomeusz G, Dalby KN, Bartholomeusz C. Xie X, et al. Among authors: dalby kn. Cancer Res Commun. 2023 Jun 20;3(6):1078-1092. doi: 10.1158/2767-9764.CRC-22-0330. eCollection 2023 Jun. Cancer Res Commun. 2023. PMID: 37377604 Free PMC article.
Fluorescent peptide assays for protein kinases.
Devkota AK, Kaoud TS, Warthaka M, Dalby KN. Devkota AK, et al. Among authors: dalby kn. Curr Protoc Mol Biol. 2010 Jul;Chapter 18:Unit 18.17. doi: 10.1002/0471142727.mb1817s91. Curr Protoc Mol Biol. 2010. PMID: 20583097 Free PMC article.
Solution NMR insights into docking interactions involving inactive ERK2.
Piserchio A, Warthaka M, Devkota AK, Kaoud TS, Lee S, Abramczyk O, Ren P, Dalby KN, Ghose R. Piserchio A, et al. Among authors: dalby kn. Biochemistry. 2011 May 10;50(18):3660-72. doi: 10.1021/bi2000559. Epub 2011 Apr 19. Biochemistry. 2011. PMID: 21449613 Free PMC article.
162 results