Pyke C - Search Results

1

Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist.

Buckley ST, Bækdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rønne J, Madsen KG, Schéele SG, Alanentalo T, Kirk RK, Pedersen BL, Skyggebjerg RB, Benie AJ, Strauss HM, Wahlund PO, Bjerregaard S, Farkas E, Fekete C, Søndergaard FL, Borregaard J, Hartoft-Nielsen ML, Knudsen LB. Buckley ST, et al. Among authors: pyke c. Sci Transl Med. 2018 Nov 14;10(467):eaar7047. doi: 10.1126/scitranslmed.aar7047. Sci Transl Med. 2018. PMID: 30429357 Clinical Trial.

2

The glucagon-like peptide-1 receptor--or not?

Pyke C, Knudsen LB. Pyke C, et al. Endocrinology. 2013 Jan;154(1):4-8. doi: 10.1210/en.2012-2124. Endocrinology. 2013. PMID: 23267050 No abstract available.

3

GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody.

Pyke C, Heller RS, Kirk RK, Ørskov C, Reedtz-Runge S, Kaastrup P, Hvelplund A, Bardram L, Calatayud D, Knudsen LB. Pyke C, et al. Endocrinology. 2014 Apr;155(4):1280-90. doi: 10.1210/en.2013-1934. Epub 2014 Jan 27. Endocrinology. 2014. PMID: 24467746

4

Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain.

Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, Knudsen LB, Vrang N, Grove KL. Heppner KM, et al. Among authors: pyke c. Endocrinology. 2015 Jan;156(1):255-67. doi: 10.1210/en.2014-1675. Endocrinology. 2015. PMID: 25380238 Free PMC article.

5

The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease.

Hansen HH, Fabricius K, Barkholt P, Niehoff ML, Morley JE, Jelsing J, Pyke C, Knudsen LB, Farr SA, Vrang N. Hansen HH, et al. Among authors: pyke c. J Alzheimers Dis. 2015;46(4):877-88. doi: 10.3233/JAD-143090. J Alzheimers Dis. 2015. PMID: 25869785 Free PMC article.

6

The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy.

Hansen HH, Barkholt P, Fabricius K, Jelsing J, Terwel D, Pyke C, Knudsen LB, Vrang N. Hansen HH, et al. Among authors: pyke c. Brain Res. 2016 Mar 1;1634:158-170. doi: 10.1016/j.brainres.2015.12.052. Epub 2015 Dec 31. Brain Res. 2016. PMID: 26746341

7

Long-acting glucagon-like peptide-1 receptor agonists have direct access to and effects on pro-opiomelanocortin/cocaine- and amphetamine-stimulated transcript neurons in the mouse hypothalamus.

Knudsen LB, Secher A, Hecksher-Sørensen J, Pyke C. Knudsen LB, et al. Among authors: pyke c. J Diabetes Investig. 2016 Apr;7 Suppl 1(Suppl 1):56-63. doi: 10.1111/jdi.12463. Epub 2016 Apr 18. J Diabetes Investig. 2016. PMID: 27186357 Free PMC article. Review.

8

Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease.

Hansen HH, Fabricius K, Barkholt P, Mikkelsen JD, Jelsing J, Pyke C, Knudsen LB, Vrang N. Hansen HH, et al. Among authors: pyke c. Brain Res. 2016 Sep 1;1646:354-365. doi: 10.1016/j.brainres.2016.05.038. Epub 2016 May 24. Brain Res. 2016. PMID: 27233809

9

Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.

Hansen HH, Fabricius K, Barkholt P, Kongsbak-Wismann P, Schlumberger C, Jelsing J, Terwel D, Termont A, Pyke C, Knudsen LB, Vrang N. Hansen HH, et al. Among authors: pyke c. PLoS One. 2016 Jul 15;11(7):e0158205. doi: 10.1371/journal.pone.0158205. eCollection 2016. PLoS One. 2016. PMID: 27421117 Free PMC article.

10

GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation.

Bang-Berthelsen CH, Holm TL, Pyke C, Simonsen L, Søkilde R, Pociot F, Heller RS, Folkersen L, Kvist PH, Jackerott M, Fleckner J, Vilién M, Knudsen LB, Heding A, Frederiksen KS. Bang-Berthelsen CH, et al. Among authors: pyke c. Inflamm Bowel Dis. 2016 Sep;22(9):2078-97. doi: 10.1097/MIB.0000000000000847. Inflamm Bowel Dis. 2016. PMID: 27542128

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