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Disrupting the CD95-PLCγ1 interaction prevents Th17-driven inflammation.
Poissonnier A, Guégan JP, Nguyen HT, Best D, Levoin N, Kozlov G, Gehring K, Pineau R, Jouan F, Morere L, Martin S, Thomas M, Lazaro E, Douchet I, Ducret T, van de Weghe P, Blanco P, Jean M, Vacher P, Legembre P. Poissonnier A, et al. Among authors: morere l. Nat Chem Biol. 2018 Dec;14(12):1079-1089. doi: 10.1038/s41589-018-0162-9. Epub 2018 Nov 14. Nat Chem Biol. 2018. PMID: 30429604
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.
Poissonnier A, Sanséau D, Le Gallo M, Malleter M, Levoin N, Viel R, Morere L, Penna A, Blanco P, Dupuy A, Poizeau F, Fautrel A, Seneschal J, Jouan F, Ritz J, Forcade E, Rioux N, Contin-Bordes C, Ducret T, Vacher AM, Barrow PA, Flynn RJ, Vacher P, Legembre P. Poissonnier A, et al. Among authors: morere l. Immunity. 2016 Jul 19;45(1):209-23. doi: 10.1016/j.immuni.2016.06.028. Immunity. 2016. PMID: 27438772 Free PMC article.