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Page 1
RNAi modulation of placental sFLT1 for the treatment of preeclampsia.
Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, Zsengeller ZK, Hennessy A, Karumanchi SA, Moore MJ, Khvorova A. Turanov AA, et al. Among authors: karumanchi sa. Nat Biotechnol. 2018 Nov 19:10.1038/nbt.4297. doi: 10.1038/nbt.4297. Online ahead of print. Nat Biotechnol. 2018. PMID: 30451990 Free PMC article.
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Maynard SE, et al. Among authors: karumanchi sa. J Clin Invest. 2003 Mar;111(5):649-58. doi: 10.1172/JCI17189. J Clin Invest. 2003. PMID: 12618519 Free PMC article.
Soluble endoglin contributes to the pathogenesis of preeclampsia.
Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA. Venkatesha S, et al. Among authors: karumanchi sa. Nat Med. 2006 Jun;12(6):642-9. doi: 10.1038/nm1429. Epub 2006 Jun 4. Nat Med. 2006. PMID: 16751767
Placental expression of angiogenic factors in Trisomy 13.
Silasi M, Rana S, Powe C, Cohen B, Lim KH, Zsengellér ZK, Karumanchi SA, Stillman IE. Silasi M, et al. Among authors: karumanchi sa. Am J Obstet Gynecol. 2011 Jun;204(6):546.e1-4. doi: 10.1016/j.ajog.2011.02.027. Epub 2011 Apr 20. Am J Obstet Gynecol. 2011. PMID: 21507376
PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice.
Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A, Zsengeller ZK, Akhavan-Sharif MR, Khankin EV, Saintgeniez M, David S, Burstein D, Karumanchi SA, Stillman IE, Arany Z, Parikh SM. Tran M, et al. Among authors: karumanchi sa. J Clin Invest. 2011 Oct;121(10):4003-14. doi: 10.1172/JCI58662. Epub 2011 Sep 1. J Clin Invest. 2011. PMID: 21881206 Free PMC article.
Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating soluble fms-like tyrosine kinase 1 in preeclampsia.
Rajakumar A, Cerdeira AS, Rana S, Zsengeller Z, Edmunds L, Jeyabalan A, Hubel CA, Stillman IE, Parikh SM, Karumanchi SA. Rajakumar A, et al. Among authors: karumanchi sa. Hypertension. 2012 Feb;59(2):256-64. doi: 10.1161/HYPERTENSIONAHA.111.182170. Epub 2012 Jan 3. Hypertension. 2012. PMID: 22215706 Free PMC article.
Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z. Patten IS, et al. Among authors: karumanchi sa. Nature. 2012 May 9;485(7398):333-8. doi: 10.1038/nature11040. Nature. 2012. PMID: 22596155 Free PMC article.
Transcriptional patterns in peritoneal tissue of encapsulating peritoneal sclerosis, a complication of chronic peritoneal dialysis.
Reimold FR, Braun N, Zsengellér ZK, Stillman IE, Karumanchi SA, Toka HR, Latus J, Fritz P, Biegger D, Segerer S, Alscher MD, Bhasin MK, Alper SL. Reimold FR, et al. Among authors: karumanchi sa. PLoS One. 2013;8(2):e56389. doi: 10.1371/journal.pone.0056389. Epub 2013 Feb 13. PLoS One. 2013. PMID: 23418565 Free PMC article.
363 results