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Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition.
Mboge MY, Chen Z, Wolff A, Mathias JV, Tu C, Brown KD, Bozdag M, Carta F, Supuran CT, McKenna R, Frost SC. Mboge MY, et al. Among authors: chen z. PLoS One. 2018 Nov 19;13(11):e0207417. doi: 10.1371/journal.pone.0207417. eCollection 2018. PLoS One. 2018. PMID: 30452451 Free PMC article.
β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.
Cai J, Qi X, Kociok N, Skosyrski S, Emilio A, Ruan Q, Han S, Liu L, Chen Z, Bowes Rickman C, Golde T, Grant MB, Saftig P, Serneels L, de Strooper B, Joussen AM, Boulton ME. Cai J, et al. Among authors: chen z. EMBO Mol Med. 2012 Sep;4(9):980-91. doi: 10.1002/emmm.201101084. Epub 2012 Aug 20. EMBO Mol Med. 2012. PMID: 22903875 Free PMC article.
Supercharging Prions via Amyloid-Selective Lysine Acetylation.
Baumer KM, Cook CD, Zahler CT, Beard AA, Chen Z, Koone JC, Dashnaw CM, Villacob RA, Solouki T, Wood JL, Borchelt DR, Shaw BF. Baumer KM, et al. Among authors: chen z. Angew Chem Int Ed Engl. 2021 Jun 25;60(27):15069-15079. doi: 10.1002/anie.202103548. Epub 2021 May 26. Angew Chem Int Ed Engl. 2021. PMID: 33876528
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