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Animal models of multiple sclerosis: From rodents to zebrafish.
Burrows DJ, McGown A, Jain SA, De Felice M, Ramesh TM, Sharrack B, Majid A. Burrows DJ, et al. Among authors: mcgown a. Mult Scler. 2019 Mar;25(3):306-324. doi: 10.1177/1352458518805246. Epub 2018 Oct 15. Mult Scler. 2019. PMID: 30319015 Review.
The effect of hyperglycemia on neurovascular coupling and cerebrovascular patterning in zebrafish.
Chhabria K, Plant K, Bandmann O, Wilkinson RN, Martin C, Kugler E, Armitage PA, Santoscoy PL, Cunliffe VT, Huisken J, McGown A, Ramesh T, Chico TJ, Howarth C. Chhabria K, et al. Among authors: mcgown a. J Cereb Blood Flow Metab. 2020 Feb;40(2):298-313. doi: 10.1177/0271678X18810615. Epub 2018 Nov 6. J Cereb Blood Flow Metab. 2020. PMID: 30398083 Free PMC article.
Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis.
Boddy S, Islam M, Moll T, Kurz J, Burrows D, McGown A, Bhargava A, Julian TH, Harvey C, Marshall JN, Hall BP, Allen SP, Kenna KP, Sanderson E, Zhang S, Ramesh T, Snyder MP, Shaw PJ, McDermott C, Cooper-Knock J. Boddy S, et al. Among authors: mcgown a. Brain Commun. 2022 Mar 17;4(2):fcac069. doi: 10.1093/braincomms/fcac069. eCollection 2022. Brain Commun. 2022. PMID: 35441136 Free PMC article.
Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo.
Kempthorne L, Vaizoglu D, Cammack AJ, Carcolé M, Roberts MJ, Mikheenko A, Fisher A, Suklai P, Muralidharan B, Kroll F, Moens TG, Yshii L, Verschoren S, Hölbling BV, Moreira FC, Katona E, Coneys R, de Oliveira P, Zhang YJ, Jansen K, Daughrity LM, McGown A, Ramesh TM, Van Den Bosch L, Lignani G, Rahim AA, Coyne AN, Petrucelli L, Rihel J, Isaacs AM. Kempthorne L, et al. Among authors: mcgown a. Nat Commun. 2025 Jan 8;16(1):459. doi: 10.1038/s41467-024-55550-x. Nat Commun. 2025. PMID: 39779704 Free PMC article.
130 results