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TRPV1 pore turret dictates distinct DkTx and capsaicin gating.
Geron M, Kumar R, Zhou W, Faraldo-Gómez JD, Vásquez V, Priel A. Geron M, et al. Among authors: kumar r. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11837-E11846. doi: 10.1073/pnas.1809662115. Epub 2018 Nov 21. Proc Natl Acad Sci U S A. 2018. PMID: 30463948 Free PMC article.
Protein toxins of the Echis coloratus viper venom directly activate TRPV1.
Geron M, Kumar R, Matzner H, Lahiani A, Gincberg G, Cohen G, Lazarovici P, Priel A. Geron M, et al. Among authors: kumar r. Biochim Biophys Acta Gen Subj. 2017 Mar;1861(3):615-623. doi: 10.1016/j.bbagen.2017.01.004. Epub 2017 Jan 4. Biochim Biophys Acta Gen Subj. 2017. PMID: 28063984
Activation of transient receptor potential vanilloid 1 by lipoxygenase metabolites depends on PKC phosphorylation.
Kumar R, Hazan A, Geron M, Steinberg R, Livni L, Matzner H, Priel A. Kumar R, et al. FASEB J. 2017 Mar;31(3):1238-1247. doi: 10.1096/fj.201601132R. Epub 2016 Dec 16. FASEB J. 2017. PMID: 27986808
We propose that the requirement of multiple signaling events allows subdued TRPV1 activation to evoke regulated neuronal response during inflammation.-Kumar R., Hazan, A., Geron, M., Steinberg, R., Livni, L., Matzner, H., Priel, A. Activation of transient rec …
We propose that the requirement of multiple signaling events allows subdued TRPV1 activation to evoke regulated neuronal response during inf …
Tricyclic Spirolactones as Modular TRPV1 Synthetic Agonists.
Mostinski Y, Noy G, Kumar R, Tsvelikhovsky D, Priel A. Mostinski Y, et al. Among authors: kumar r. ACS Chem Neurosci. 2017 Aug 16;8(8):1688-1696. doi: 10.1021/acschemneuro.7b00127. Epub 2017 May 25. ACS Chem Neurosci. 2017. PMID: 28520395
GTL-1, a Calcium Activated TRPM Channel, Enhances Nociception.
Cohen E, Kumar R, Zinger T, Priel A, Treinin M. Cohen E, et al. Among authors: kumar r. Front Pharmacol. 2020 Jan 17;10:1567. doi: 10.3389/fphar.2019.01567. eCollection 2019. Front Pharmacol. 2020. PMID: 32009965 Free PMC article.
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