Johnstone EKM - Search Results

1

NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing.

White CW, Johnstone EKM, See HB, Pfleger KDG. White CW, et al. Among authors: johnstone ekm. Cell Signal. 2019 Feb;54:27-34. doi: 10.1016/j.cellsig.2018.11.018. Epub 2018 Nov 22. Cell Signal. 2019. PMID: 30471466 Free article.

2

Application of BRET to monitor ligand binding to GPCRs.

Stoddart LA, Johnstone EKM, Wheal AJ, Goulding J, Robers MB, Machleidt T, Wood KV, Hill SJ, Pfleger KDG. Stoddart LA, et al. Among authors: johnstone ekm. Nat Methods. 2015 Jul;12(7):661-663. doi: 10.1038/nmeth.3398. Epub 2015 Jun 1. Nat Methods. 2015. PMID: 26030448 Free PMC article.

3

Bioluminescence Resonance Energy Transfer Approaches to Discover Bias in GPCR Signaling.

Johnstone EK, Pfleger KD. Johnstone EK, et al. Methods Mol Biol. 2015;1335:191-204. doi: 10.1007/978-1-4939-2914-6_13. Methods Mol Biol. 2015. PMID: 26260602

4

Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.

White CW, Vanyai HK, See HB, Johnstone EKM, Pfleger KDG. White CW, et al. Among authors: johnstone ekm. Sci Rep. 2017 Jun 9;7(1):3187. doi: 10.1038/s41598-017-03486-2. Sci Rep. 2017. PMID: 28600500 Free PMC article.

5

NanoBRET: The Bright Future of Proximity-Based Assays.

Dale NC, Johnstone EKM, White CW, Pfleger KDG. Dale NC, et al. Among authors: johnstone ekm. Front Bioeng Biotechnol. 2019 Mar 26;7:56. doi: 10.3389/fbioe.2019.00056. eCollection 2019. Front Bioeng Biotechnol. 2019. PMID: 30972335 Free PMC article. Review.

6

Investigation of Receptor Heteromers Using NanoBRET Ligand Binding.

Johnstone EKM, See HB, Abhayawardana RS, Song A, Rosengren KJ, Hill SJ, Pfleger KDG. Johnstone EKM, et al. Int J Mol Sci. 2021 Jan 22;22(3):1082. doi: 10.3390/ijms22031082. Int J Mol Sci. 2021. PMID: 33499147 Free PMC article.

7

Profiling novel pharmacology of receptor complexes using Receptor-HIT.

Johnstone EKM, Pfleger KDG. Johnstone EKM, et al. Biochem Soc Trans. 2021 Aug 27;49(4):1555-1565. doi: 10.1042/BST20201110. Biochem Soc Trans. 2021. PMID: 34436548 Free PMC article. Review.

8

Receptor-Heteromer Investigation Technology and its application using BRET.

Johnstone EK, Pfleger KD. Johnstone EK, et al. Front Endocrinol (Lausanne). 2012 Aug 22;3:101. doi: 10.3389/fendo.2012.00101. eCollection 2012. Front Endocrinol (Lausanne). 2012. PMID: 22936924 Free PMC article.

9

Functional interaction between angiotensin II receptor type 1 and chemokine (C-C motif) receptor 2 with implications for chronic kidney disease.

Ayoub MA, Zhang Y, Kelly RS, See HB, Johnstone EK, McCall EA, Williams JH, Kelly DJ, Pfleger KD. Ayoub MA, et al. PLoS One. 2015 Mar 25;10(3):e0119803. doi: 10.1371/journal.pone.0119803. eCollection 2015. PLoS One. 2015. PMID: 25807547 Free PMC article.

10

BRET-based assay to monitor EGFR transactivation by the AT₁R reveals G_q/11 protein-independent activation and AT₁R-EGFR complexes.

O'Brien SL, Johnstone EKM, Devost D, Conroy J, Reichelt ME, Purdue BW, Ayoub MA, Kawai T, Inoue A, Eguchi S, Hébert TE, Pfleger KDG, Thomas WG. O'Brien SL, et al. Among authors: johnstone ekm. Biochem Pharmacol. 2018 Dec;158:232-242. doi: 10.1016/j.bcp.2018.10.017. Epub 2018 Oct 19. Biochem Pharmacol. 2018. PMID: 30347205 Free PMC article.

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