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Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae.
Hewitt CS, Abutaleb NS, Elhassanny AEM, Nocentini A, Cao X, Amos DP, Youse MS, Holly KJ, Marapaka AK, An W, Kaur J, Krabill AD, Elkashif A, Elgammal Y, Graboski AL, Supuran CT, Seleem MN, Flaherty DP. Hewitt CS, et al. Among authors: flaherty dp. ACS Infect Dis. 2021 Jul 9;7(7):1969-1984. doi: 10.1021/acsinfecdis.1c00055. Epub 2021 Mar 25. ACS Infect Dis. 2021. PMID: 33765392 Free PMC article.
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
Imhoff RD, Patel R, Safdar MH, Jones HBL, Pinto-Fernandez A, Vendrell I, Chen H, Muli CS, Krabill AD, Kessler BM, Wendt MK, Das C, Flaherty DP. Imhoff RD, et al. Among authors: flaherty dp. J Med Chem. 2024 Mar 28;67(6):4496-4524. doi: 10.1021/acs.jmedchem.3c01661. Epub 2024 Mar 15. J Med Chem. 2024. PMID: 38488146
Biochemical pharmacology of adenylyl cyclases in cancer.
Chandra Jena B, Flaherty DP, O'Brien VP, Watts VJ. Chandra Jena B, et al. Among authors: flaherty dp. Biochem Pharmacol. 2024 Oct;228:116160. doi: 10.1016/j.bcp.2024.116160. Epub 2024 Mar 24. Biochem Pharmacol. 2024. PMID: 38522554 Review.
59 results