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Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons.
Stakenborg N, Labeeuw E, Gomez-Pinilla PJ, De Schepper S, Aerts R, Goverse G, Farro G, Appeltans I, Meroni E, Stakenborg M, Viola MF, Gonzalez-Dominguez E, Bosmans G, Alpizar YA, Wolthuis A, D'Hoore A, Van Beek K, Verheijden S, Verhaegen M, Derua R, Waelkens E, Moretti M, Gotti C, Augustijns P, Talavera K, Vanden Berghe P, Matteoli G, Boeckxstaens GE. Stakenborg N, et al. Among authors: vanden berghe p. Gut. 2019 Aug;68(8):1406-1416. doi: 10.1136/gutjnl-2018-317263. Epub 2018 Nov 24. Gut. 2019. PMID: 30472681 Free PMC article. Clinical Trial.
Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome.
Wouters MM, Balemans D, Van Wanrooy S, Dooley J, Cibert-Goton V, Alpizar YA, Valdez-Morales EE, Nasser Y, Van Veldhoven PP, Vanbrabant W, Van der Merwe S, Mols R, Ghesquière B, Cirillo C, Kortekaas I, Carmeliet P, Peetermans WE, Vermeire S, Rutgeerts P, Augustijns P, Hellings PW, Belmans A, Vanner S, Bulmer DC, Talavera K, Vanden Berghe P, Liston A, Boeckxstaens GE. Wouters MM, et al. Among authors: vanden berghe p. Gastroenterology. 2016 Apr;150(4):875-87.e9. doi: 10.1053/j.gastro.2015.12.034. Epub 2016 Jan 2. Gastroenterology. 2016. PMID: 26752109 Clinical Trial.
Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS.
Balemans D, Mondelaers SU, Cibert-Goton V, Stakenborg N, Aguilera-Lizarraga J, Dooley J, Liston A, Bulmer DC, Vanden Berghe P, Boeckxstaens GE, Wouters MM. Balemans D, et al. Among authors: vanden berghe p. Sci Rep. 2017 Oct 19;7(1):13606. doi: 10.1038/s41598-017-12618-7. Sci Rep. 2017. PMID: 29051514 Free PMC article.
Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.
De Schepper S, Verheijden S, Aguilera-Lizarraga J, Viola MF, Boesmans W, Stakenborg N, Voytyuk I, Schmidt I, Boeckx B, Dierckx de Casterlé I, Baekelandt V, Gonzalez Dominguez E, Mack M, Depoortere I, De Strooper B, Sprangers B, Himmelreich U, Soenen S, Guilliams M, Vanden Berghe P, Jones E, Lambrechts D, Boeckxstaens G. De Schepper S, et al. Among authors: vanden berghe p. Cell. 2018 Oct 4;175(2):400-415.e13. doi: 10.1016/j.cell.2018.07.048. Epub 2018 Aug 30. Cell. 2018. PMID: 30173915 Free article.
Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome.
Balemans D, Aguilera-Lizarraga J, Florens MV, Jain P, Denadai-Souza A, Viola MF, Alpizar YA, Van Der Merwe S, Vanden Berghe P, Talavera K, Vanner S, Wouters MM, Boeckxstaens GE. Balemans D, et al. Among authors: vanden berghe p. Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G338-G349. doi: 10.1152/ajpgi.00116.2018. Epub 2019 Jan 10. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30629470 Free article.
Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.
De Schepper S, Verheijden S, Aguilera-Lizarraga J, Viola MF, Boesmans W, Stakenborg N, Voytyuk I, Schmidt I, Boeckx B, Dierckx de Casterlé I, Baekelandt V, Gonzalez Dominguez E, Mack M, Depoortere I, De Strooper B, Sprangers B, Himmelreich U, Soenen S, Guilliams M, Vanden Berghe P, Jones E, Lambrechts D, Boeckxstaens G. De Schepper S, et al. Among authors: vanden berghe p. Cell. 2019 Jan 24;176(3):676. doi: 10.1016/j.cell.2019.01.010. Cell. 2019. PMID: 30682373 Free article. No abstract available.
169 results