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Page 1
Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion.
Bürgel PH, Marina CL, Saavedra PHV, Albuquerque P, de Oliveira SAM, Veloso Janior PHH, de Castro RA, Heyman HM, Coelho C, Cordero RJB, Casadevall A, Nosanchuk JD, Nakayasu ES, May RC, Tavares AH, Bocca AL. Bürgel PH, et al. Among authors: saavedra phv. Mediators Inflamm. 2020 Dec 3;2020:3412763. doi: 10.1155/2020/3412763. eCollection 2020. Mediators Inflamm. 2020. PMID: 33380899 Free PMC article.
Immunology: Gut sensor halts viral attack.
Saavedra PHV, Lamkanfi M. Saavedra PHV, et al. Nature. 2017 Jun 29;546(7660):606-608. doi: 10.1038/nature23090. Epub 2017 Jun 21. Nature. 2017. PMID: 28636602 No abstract available.
IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D.
Kiss M, Vande Walle L, Saavedra PHV, Lebegge E, Van Damme H, Murgaski A, Qian J, Ehling M, Pretto S, Bolli E, Keirsse J, Bardet PMR, Arnouk SM, Elkrim Y, Schmoetten M, Brughmans J, Debraekeleer A, Fossoul A, Boon L, Raes G, van Loo G, Lambrechts D, Mazzone M, Beschin A, Wullaert A, Lamkanfi M, Van Ginderachter JA, Laoui D. Kiss M, et al. Among authors: saavedra phv. Cancer Immunol Res. 2021 Mar;9(3):309-323. doi: 10.1158/2326-6066.CIR-20-0431. Epub 2020 Dec 23. Cancer Immunol Res. 2021. PMID: 33361087
Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice.
Dufies O, Doye A, Courjon J, Torre C, Michel G, Loubatier C, Jacquel A, Chaintreuil P, Majoor A, Guinamard RR, Gallerand A, Saavedra PHV, Verhoeyen E, Rey A, Marchetti S, Ruimy R, Czerucka D, Lamkanfi M, Py BF, Munro P, Visvikis O, Boyer L. Dufies O, et al. Among authors: saavedra phv. Nat Microbiol. 2021 Mar;6(3):401-412. doi: 10.1038/s41564-020-00832-5. Epub 2021 Jan 11. Nat Microbiol. 2021. PMID: 33432150 Free PMC article.
Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation.
Van Gorp H, Saavedra PH, de Vasconcelos NM, Van Opdenbosch N, Vande Walle L, Matusiak M, Prencipe G, Insalaco A, Van Hauwermeiren F, Demon D, Bogaert DJ, Dullaers M, De Baere E, Hochepied T, Dehoorne J, Vermaelen KY, Haerynck F, De Benedetti F, Lamkanfi M. Van Gorp H, et al. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14384-14389. doi: 10.1073/pnas.1613156113. Epub 2016 Nov 22. Proc Natl Acad Sci U S A. 2016. PMID: 27911804 Free PMC article.
Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4.
Van Opdenbosch N, Van Gorp H, Verdonckt M, Saavedra PHV, de Vasconcelos NM, Gonçalves A, Vande Walle L, Demon D, Matusiak M, Van Hauwermeiren F, D'Hont J, Hochepied T, Krautwald S, Kanneganti TD, Lamkanfi M. Van Opdenbosch N, et al. Among authors: saavedra phv. Cell Rep. 2017 Dec 19;21(12):3427-3444. doi: 10.1016/j.celrep.2017.11.088. Cell Rep. 2017. PMID: 29262324 Free PMC article.
19 results