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The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, Hosfield DJ, Chandarlapaty S, Tajkhorshid E, Nettles KW, Griffin PR, Shen Y, Katzenellenbogen JA, Brown M, Greene GL. Fanning SW, et al. Among authors: katzenellenbogen ja. Elife. 2018 Nov 29;7:e37161. doi: 10.7554/eLife.37161. Elife. 2018. PMID: 30489256 Free PMC article.
Estrogen platinum-diamine complexes: preparation of a non-steroidal estrogen platinum-diamine complex labeled with platinum-191 and a study of its binding to the estrogen receptor in vitro and its tissue distribution in vivo.
DiZio JP, Carlson KE, Bannochie CJ, Welch MJ, Von Angerer E, Katzenellenbogen JA. DiZio JP, et al. Among authors: katzenellenbogen ja. J Steroid Biochem Mol Biol. 1992 May;42(3-4):363-73. doi: 10.1016/0960-0760(92)90141-5. J Steroid Biochem Mol Biol. 1992. PMID: 1606047
516 results