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170 results

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Page 1
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.
Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC. Haliyur R, et al. Among authors: harlan dm. J Clin Invest. 2019 Jan 2;129(1):246-251. doi: 10.1172/JCI121994. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30507613 Free PMC article.
Humanized mice for the study of type 1 and type 2 diabetes.
Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD. Greiner DL, et al. Among authors: harlan dm. Ann N Y Acad Sci. 2011 Dec;1245:55-8. doi: 10.1111/j.1749-6632.2011.06318.x. Ann N Y Acad Sci. 2011. PMID: 22211980 Free PMC article.
The pancreatic β-cell transcriptome and integrated-omics.
Blodgett DM, Cura AJ, Harlan DM. Blodgett DM, et al. Among authors: harlan dm. Curr Opin Endocrinol Diabetes Obes. 2014 Apr;21(2):83-8. doi: 10.1097/MED.0000000000000051. Curr Opin Endocrinol Diabetes Obes. 2014. PMID: 24526012 Free PMC article. Review.
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT Jr, Powers AC, Gu G, Stein R. Conrad E, et al. Among authors: harlan dm. Am J Physiol Endocrinol Metab. 2016 Jan 1;310(1):E91-E102. doi: 10.1152/ajpendo.00285.2015. Epub 2015 Nov 10. Am J Physiol Endocrinol Metab. 2016. PMID: 26554594 Free PMC article.
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.
Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K. Delong T, et al. Among authors: harlan dm. Science. 2016 Feb 12;351(6274):711-4. doi: 10.1126/science.aad2791. Science. 2016. PMID: 26912858 Free PMC article.
Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Babon JA, et al. Among authors: harlan dm. Nat Med. 2016 Dec;22(12):1482-1487. doi: 10.1038/nm.4203. Epub 2016 Oct 31. Nat Med. 2016. PMID: 27798614 Free PMC article.
Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Babon JA, et al. Among authors: harlan dm. Nat Med. 2017 Feb 7;23(2):264. doi: 10.1038/nm0217-264a. Nat Med. 2017. PMID: 28170374 No abstract available.
170 results