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A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL. Zhang J, et al. Among authors: dere r. Nat Cell Biol. 2013 Oct;15(10):1186-96. doi: 10.1038/ncb2822. Epub 2013 Aug 18. Nat Cell Biol. 2013. PMID: 23955302 Free PMC article.
ATM functions at the peroxisome to induce pexophagy in response to ROS.
Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. Zhang J, et al. Among authors: dere r. Nat Cell Biol. 2015 Oct;17(10):1259-1269. doi: 10.1038/ncb3230. Epub 2015 Sep 7. Nat Cell Biol. 2015. PMID: 26344566 Free PMC article.
Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Park IY, Powell RT, Tripathi DN, Dere R, Ho TH, Blasius TL, Chiang YC, Davis IJ, Fahey CC, Hacker KE, Verhey KJ, Bedford MT, Jonasch E, Rathmell WK, Walker CL. Park IY, et al. Among authors: dere r. Cell. 2016 Aug 11;166(4):950-962. doi: 10.1016/j.cell.2016.07.005. Cell. 2016. PMID: 27518565 Free PMC article.
SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.
Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK. Chiang YC, et al. Among authors: dere r. Cancer Res. 2018 Jun 15;78(12):3135-3146. doi: 10.1158/0008-5472.CAN-17-3460. Epub 2018 May 3. Cancer Res. 2018. PMID: 29724720 Free PMC article.
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL. Seervai RNH, et al. Among authors: dere r. Sci Adv. 2020 Oct 2;6(40):eabb7854. doi: 10.1126/sciadv.abb7854. Print 2020 Oct. Sci Adv. 2020. PMID: 33008892 Free PMC article.
65 results