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Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds.
Mansour TA, Lucot K, Konopelski SE, Dickinson PJ, Sturges BK, Vernau KL, Choi S, Stern JA, Thomasy SM, Döring S, Verstraete FJM, Johnson EG, York D, Rebhun RB, Ho HH, Brown CT, Bannasch DL. Mansour TA, et al. Among authors: choi s. PLoS Genet. 2018 Dec 6;14(12):e1007850. doi: 10.1371/journal.pgen.1007850. eCollection 2018 Dec. PLoS Genet. 2018. PMID: 30521570 Free PMC article.
Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling.
Konopelski Snavely SE, Susman MW, Kunz RC, Tan J, Srinivasan S, Cohen MD, Okada K, Lamb H, Choi SS, Karuna EP, Scales MK, Gygi SP, Greenberg ME, Ho HH. Konopelski Snavely SE, et al. Among authors: choi ss. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2104944118. doi: 10.1073/pnas.2104944118. Proc Natl Acad Sci U S A. 2021. PMID: 34135125 Free PMC article.
Unsupervised deep learning of electrocardiograms enables scalable human disease profiling.
Friedman SF, Khurshid S, Venn RA, Wang X, Diamant N, Di Achille P, Weng LC, Choi SH, Reeder C, Pirruccello JP, Singh P, Lau ES, Philippakis A, Anderson CD, Maddah M, Batra P, Ellinor PT, Ho JE, Lubitz SA. Friedman SF, et al. Among authors: choi sh. NPJ Digit Med. 2025 Jan 12;8(1):23. doi: 10.1038/s41746-024-01418-9. NPJ Digit Med. 2025. PMID: 39799251
Post-COVID metabolic enzyme alterations in K18-hACE2 mice exacerbate alcohol-induced liver injury through transcriptional regulation.
Park S, Lee YW, Choi S, Jo H, Kim N, Cho S, Lee E, Choi EB, Park I, Jeon Y, Noh H, Seok SH, Oh SH, Choi YK, Kwon HK, Seo JY, Nam KT, Park JW, Choi KS, Lee HY, Yun JW, Seong JK. Park S, et al. Among authors: choi s. Free Radic Biol Med. 2025 Jan 9:S0891-5849(25)00015-2. doi: 10.1016/j.freeradbiomed.2025.01.015. Online ahead of print. Free Radic Biol Med. 2025. PMID: 39798903
Durvalumab with or without bevacizumab with transarterial chemoembolisation in hepatocellular carcinoma (EMERALD-1): a multiregional, randomised, double-blind, placebo-controlled, phase 3 study.
Sangro B, Kudo M, Erinjeri JP, Qin S, Ren Z, Chan SL, Arai Y, Heo J, Mai A, Escobar J, Lopez Chuken YA, Yoon JH, Tak WY, Breder VV, Suttichaimongkol T, Bouattour M, Lin SM, Peron JM, Nguyen QT, Yan L, Chiu CF, Santos FA, Veluvolu A, Thungappa SC, Matos M, Żotkiewicz M, Udoye SI, Kurland JF, Cohen GJ, Lencioni R; EMERALD-1 Investigators. Sangro B, et al. Lancet. 2025 Jan 8:S0140-6736(24)02551-0. doi: 10.1016/S0140-6736(24)02551-0. Online ahead of print. Lancet. 2025. PMID: 39798579
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