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729 results

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Page 1
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. Jessen WJ, et al. Among authors: kim mo. J Clin Invest. 2013 Jan;123(1):340-7. doi: 10.1172/JCI60578. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221341 Free PMC article. Clinical Trial.
Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.
Wu J, Keng VW, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, Dombi E, Levy DE, Huang G, Cancelas JA, Stemmer-Rachamimov AO, Spinner RJ, Largaespada DA, Ratner N. Wu J, et al. Among authors: kim mo. Cell Rep. 2016 Mar 1;14(8):1979-90. doi: 10.1016/j.celrep.2016.01.074. Epub 2016 Feb 18. Cell Rep. 2016. PMID: 26904939 Free PMC article.
Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice.
Fletcher JS, Wu J, Jessen WJ, Pundavela J, Miller JA, Dombi E, Kim MO, Rizvi TA, Chetal K, Salomonis N, Ratner N. Fletcher JS, et al. Among authors: kim mo. JCI Insight. 2019 Feb 7;4(3):e98601. doi: 10.1172/jci.insight.98601. JCI Insight. 2019. PMID: 30728335 Free PMC article.
RUNX represses Pmp22 to drive neurofibromagenesis.
Hall A, Choi K, Liu W, Rose J, Zhao C, Yu Y, Na Y, Cai Y, Coover RA, Lin Y, Dombi E, Kim M, Levanon D, Groner Y, Boscolo E, Pan D, Liu PP, Lu QR, Ratner N, Huang G, Wu J. Hall A, et al. Sci Adv. 2019 Apr 24;5(4):eaau8389. doi: 10.1126/sciadv.aau8389. eCollection 2019 Apr. Sci Adv. 2019. PMID: 31032403 Free PMC article.
MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK.
Na Y, Hall A, Choi K, Hu L, Rose J, Coover RA, Miller A, Hennigan RF, Dombi E, Kim MO, Subramanian S, Ratner N, Wu J. Na Y, et al. Among authors: kim mo. Oncogene. 2021 Feb;40(5):951-963. doi: 10.1038/s41388-020-01581-9. Epub 2020 Dec 8. Oncogene. 2021. PMID: 33293695 Free PMC article.
729 results