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Page 1
Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors.
Collie GW, Koh CM, O'Neill DJ, Stubbs CJ, Khurana P, Eddershaw A, Snijder A, Mauritzson F, Barlind L, Dale IL, Shaw J, Phillips C, Hennessy EJ, Cheung T, Narvaez AJ. Collie GW, et al. Among authors: narvaez aj. ACS Med Chem Lett. 2019 Aug 2;10(9):1322-1327. doi: 10.1021/acsmedchemlett.9b00276. eCollection 2019 Sep 12. ACS Med Chem Lett. 2019. PMID: 31531204 Free PMC article.
Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1.
Huggins DJ, Hardwick BS, Sharma P, Emery A, Laraia L, Zhang F, Narvaez AJ, Roberts-Thomson M, Crooks AT, Boyle RG, Boyce R, Walker DW, Mateu N, McKenzie GJ, Spring DR, Venkitaraman AR. Huggins DJ, et al. Among authors: narvaez aj. ACS Omega. 2019 Dec 24;5(1):822-831. doi: 10.1021/acsomega.9b03626. eCollection 2020 Jan 14. ACS Omega. 2019. PMID: 31956833 Free PMC article.
NF-κB signaling mediates acquired resistance after PARP inhibition.
Nakagawa Y, Sedukhina AS, Okamoto N, Nagasawa S, Suzuki N, Ohta T, Hattori H, Roche-Molina M, Narváez AJ, Jeyasekharan AD, Bernal JA, Sato K. Nakagawa Y, et al. Among authors: narvaez aj. Oncotarget. 2015 Feb 28;6(6):3825-39. doi: 10.18632/oncotarget.2868. Oncotarget. 2015. PMID: 25686825 Free PMC article.
Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS.
Narvaez AJ, Ber S, Crooks A, Emery A, Hardwick B, Guarino Almeida E, Huggins DJ, Perera D, Roberts-Thomson M, Azzarelli R, Hood FE, Prior IA, Walker DW, Boyce R, Boyle RG, Barker SP, Torrance CJ, McKenzie GJ, Venkitaraman AR. Narvaez AJ, et al. Cell Chem Biol. 2017 Aug 17;24(8):1017-1028.e7. doi: 10.1016/j.chembiol.2017.07.009. Epub 2017 Aug 10. Cell Chem Biol. 2017. PMID: 28807782 Free PMC article.
17 results