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Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.
Killion EA, Wang J, Yie J, Shi SD, Bates D, Min X, Komorowski R, Hager T, Deng L, Atangan L, Lu SC, Kurzeja RJM, Sivits G, Lin J, Chen Q, Wang Z, Thibault SA, Abbott CM, Meng T, Clavette B, Murawsky CM, Foltz IN, Rottman JB, Hale C, Véniant MM, Lloyd DJ. Killion EA, et al. Among authors: chen q. Sci Transl Med. 2018 Dec 19;10(472):eaat3392. doi: 10.1126/scitranslmed.aat3392. Sci Transl Med. 2018. PMID: 30567927
Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types.
Kaplan-Lefko PJ, Graves JD, Zoog SJ, Pan Y, Wall J, Branstetter DG, Moriguchi J, Coxon A, Huard JN, Xu R, Peach ML, Juan G, Kaufman S, Chen Q, Bianchi A, Kordich JJ, Ma M, Foltz IN, Gliniak BC. Kaplan-Lefko PJ, et al. Among authors: chen q. Cancer Biol Ther. 2010 Apr 15;9(8):618-31. doi: 10.4161/cbt.9.8.11264. Epub 2010 Apr 20. Cancer Biol Ther. 2010. PMID: 20150762 Free article.
Functional and Nonclinical Similarity of ABP 980, a Biosimilar of Trastuzumab.
Jassem S, Wang W, Sweet H, Manoukian R, Chow V, Kanakaraj P, Hutterer KM, Kuhns S, Foltz IN, Chen Q, Ferbas J, McBride HJ. Jassem S, et al. Among authors: chen q. Pharm Res. 2019 Nov 6;36(12):177. doi: 10.1007/s11095-019-2702-8. Pharm Res. 2019. PMID: 31696314 Free PMC article.
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