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Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Haji-Ghassemi O, Müller-Loennies S, Brooks CL, MacKenzie CR, Caveney N, Van Petegem F, Brade L, Kosma P, Brade H, Evans SV. Haji-Ghassemi O, et al. Among authors: brooks cl. Biochemistry. 2019 Feb 12;58(6):714-726. doi: 10.1021/acs.biochem.8b00318. Epub 2019 Jan 10. Biochemistry. 2019. PMID: 30571096
Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Brooks CL, Blackler RJ, Gerstenbruch S, Kosma P, Müller-Loennies S, Brade H, Evans SV. Brooks CL, et al. Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1250-8. doi: 10.1107/S0907444908033453. Epub 2008 Nov 18. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 19018101
Antibody recognition of a unique tumor-specific glycopeptide antigen.
Brooks CL, Schietinger A, Borisova SN, Kufer P, Okon M, Hirama T, Mackenzie CR, Wang LX, Schreiber H, Evans SV. Brooks CL, et al. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10056-61. doi: 10.1073/pnas.0915176107. Epub 2010 May 17. Proc Natl Acad Sci U S A. 2010. PMID: 20479270 Free PMC article.
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.
Gomery K, Müller-Loennies S, Brooks CL, Brade L, Kosma P, Di Padova F, Brade H, Evans SV. Gomery K, et al. Among authors: brooks cl. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20877-82. doi: 10.1073/pnas.1209253109. Epub 2012 Nov 26. Proc Natl Acad Sci U S A. 2012. PMID: 23184990 Free PMC article.
478 results