Chan LK - Search Results

1

APOBEC3B promotes hepatocarcinogenesis and metastasis through novel deaminase-independent activity.

Ma W, Ho DW, Sze KM, Tsui YM, Chan LK, Lee JM, Ng IO. Ma W, et al. Among authors: chan lk. Mol Carcinog. 2019 May;58(5):643-653. doi: 10.1002/mc.22956. Epub 2019 Jan 6. Mol Carcinog. 2019. PMID: 30575099

2

Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma.

Ko FC, Yeung YS, Wong CM, Chan LK, Poon RT, Ng IO, Yam JW. Ko FC, et al. Among authors: chan lk. Liver Int. 2010 Jan;30(1):139-48. doi: 10.1111/j.1478-3231.2009.02133.x. Epub 2009 Oct 27. Liver Int. 2010. PMID: 19874489

3

Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis.

Tse EY, Ko FC, Tung EK, Chan LK, Lee TK, Ngan ES, Man K, Wong AS, Ng IO, Yam JW. Tse EY, et al. Among authors: chan lk. J Pathol. 2012 Mar;226(4):645-53. doi: 10.1002/path.3957. Epub 2012 Jan 4. J Pathol. 2012. PMID: 22072235

4

Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma.

Chan LK, Chiu YT, Sze KM, Ng IO. Chan LK, et al. Oncotarget. 2015 Aug 28;6(25):20964-76. doi: 10.18632/oncotarget.4122. Oncotarget. 2015. PMID: 26035355 Free PMC article.

5

Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma.

Chiu YT, Wong JK, Choi SW, Sze KM, Ho DW, Chan LK, Lee JM, Man K, Cherny S, Yang WL, Wong CM, Sham PC, Ng IO. Chiu YT, et al. Among authors: chan lk. J Hepatol. 2016 Jun;64(6):1256-64. doi: 10.1016/j.jhep.2016.02.005. Epub 2016 Feb 8. J Hepatol. 2016. PMID: 26867494 Free article.

6

Down-regulation of TIMP2 by HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma.

Kai AK, Chan LK, Lo RC, Lee JM, Wong CC, Wong JC, Ng IO. Kai AK, et al. Among authors: chan lk. Hepatology. 2016 Aug;64(2):473-87. doi: 10.1002/hep.28577. Epub 2016 Apr 30. Hepatology. 2016. PMID: 27018975 Free PMC article.

7

RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma.

Ma W, Sze KM, Chan LK, Lee JM, Wei LL, Wong CM, Lee TK, Wong CC, Ng IO. Ma W, et al. Among authors: chan lk. Oncotarget. 2016 Jul 5;7(27):41445-41459. doi: 10.18632/oncotarget.9441. Oncotarget. 2016. PMID: 27213590 Free PMC article.

8

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop.

Cui CP, Wong CC, Kai AK, Ho DW, Lau EY, Tsui YM, Chan LK, Cheung TT, Chok KS, Chan ACY, Lo RC, Lee JM, Lee TK, Ng IOL. Cui CP, et al. Among authors: chan lk, chan acy. Gut. 2017 Dec;66(12):2149-2159. doi: 10.1136/gutjnl-2016-313264. Epub 2017 Mar 3. Gut. 2017. PMID: 28258134 Free PMC article.

9

Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer.

Ho DW, Tsui YM, Sze KM, Chan LK, Cheung TT, Lee E, Sham PC, Tsui SK, Lee TK, Ng IO. Ho DW, et al. Among authors: chan lk. Cancer Lett. 2019 Sep 10;459:176-185. doi: 10.1016/j.canlet.2019.06.002. Epub 2019 Jun 10. Cancer Lett. 2019. PMID: 31195060

10

Hepatitis B Virus-Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma.

Sze KM, Ho DW, Chiu YT, Tsui YM, Chan LK, Lee JM, Chok KS, Chan AC, Tang CN, Tang VW, Lo IL, Yau DT, Cheung TT, Ng IO. Sze KM, et al. Among authors: chan lk, chan ac. Hepatology. 2021 Jan;73(1):23-40. doi: 10.1002/hep.31231. Epub 2020 Nov 26. Hepatology. 2021. PMID: 32170761 Free PMC article.

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