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Safety and Tolerability of Omalizumab: A Randomized Clinical Trial of Humanized Anti-IgE Monoclonal Antibody in Systemic Lupus Erythematosus.
Hasni S, Gupta S, Davis M, Poncio E, Temesgen-Oyelakin Y, Joyal E, Fike A, Manna Z, Auh S, Shi Y, Chan D, Carlucci P, Biehl A, Dema B, Charles N, Balow JE, Waldman M, Siegel RM, Kaplan MJ, Rivera J. Hasni S, et al. Among authors: siegel rm. Arthritis Rheumatol. 2019 Jul;71(7):1135-1140. doi: 10.1002/art.40828. Epub 2019 May 8. Arthritis Rheumatol. 2019. PMID: 30597768 Free PMC article. Clinical Trial.
Distinct Functions of Autoantibodies Against Interferon in Systemic Lupus Erythematosus: A Comprehensive Analysis of Anticytokine Autoantibodies in Common Rheumatic Diseases.
Gupta S, Tatouli IP, Rosen LB, Hasni S, Alevizos I, Manna ZG, Rivera J, Jiang C, Siegel RM, Holland SM, Moutsopoulos HM, Browne SK. Gupta S, et al. Among authors: siegel rm. Arthritis Rheumatol. 2016 Jul;68(7):1677-87. doi: 10.1002/art.39607. Arthritis Rheumatol. 2016. PMID: 26815287 Free PMC article.
Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.
Zhou Y, Chen B, Mittereder N, Chaerkady R, Strain M, An LL, Rahman S, Ma W, Low CP, Chan D, Neal F, Bingham CO 3rd, Sampson K, Darrah E, Siegel RM, Hasni S, Andrade F, Vousden KA, Mustelin T, Sims GP. Zhou Y, et al. Among authors: siegel rm. Front Immunol. 2017 Sep 25;8:1200. doi: 10.3389/fimmu.2017.01200. eCollection 2017. Front Immunol. 2017. PMID: 28993780 Free PMC article.
IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE.
Wang S, Wang J, Kumar V, Karnell JL, Naiman B, Gross PS, Rahman S, Zerrouki K, Hanna R, Morehouse C, Holoweckyj N, Liu H; Autoimmunity Molecular Medicine Team; Manna Z, Goldbach-Mansky R, Hasni S, Siegel R, Sanjuan M, Streicher K, Cancro MP, Kolbeck R, Ettinger R. Wang S, et al. Nat Commun. 2018 May 1;9(1):1758. doi: 10.1038/s41467-018-03750-7. Nat Commun. 2018. PMID: 29717110 Free PMC article.
Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus.
Hudspeth K, Wang S, Wang J, Rahman S, Smith MA, Casey KA; Autoimmunity Molecular Team; Manna Z, Sanjuan M, Kolbeck R, Hasni S, Ettinger R, Siegel RM. Hudspeth K, et al. Among authors: siegel rm. Clin Exp Immunol. 2019 May;196(2):226-236. doi: 10.1111/cei.13263. Epub 2019 Mar 19. Clin Exp Immunol. 2019. PMID: 30693467 Free PMC article.
LOX-1: A potential driver of cardiovascular risk in SLE patients.
Sagar D, Gaddipati R, Ongstad EL, Bhagroo N, An LL, Wang J, Belkhodja M, Rahman S, Manna Z, Davis MA, Hasni S, Siegel R, Sanjuan M, Grimsby J, Kolbeck R, Karathanasis S, Sims GP, Gupta R. Sagar D, et al. PLoS One. 2020 Mar 17;15(3):e0229184. doi: 10.1371/journal.pone.0229184. eCollection 2020. PLoS One. 2020. PMID: 32182251 Free PMC article.
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
Jing C, Castro-Dopico T, Richoz N, Tuong ZK, Ferdinand JR, Lok LSC, Loudon KW, Banham GD, Mathews RJ, Cader Z, Fitzpatrick S, Bashant KR, Kaplan MJ, Kaser A, Johnson RS, Murphy MP, Siegel RM, Clatworthy MR. Jing C, et al. Among authors: siegel rm. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15160-15171. doi: 10.1073/pnas.2000943117. Epub 2020 Jun 15. Proc Natl Acad Sci U S A. 2020. PMID: 32541026 Free PMC article.
Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis.
Richoz N, Tuong ZK, Loudon KW, Patiño-Martínez E, Ferdinand JR, Portet A, Bashant KR, Thevenon E, Rucci F, Hoyler T, Junt T, Kaplan MJ, Siegel RM, Clatworthy MR. Richoz N, et al. Among authors: siegel rm. JCI Insight. 2022 Nov 8;7(21):e159751. doi: 10.1172/jci.insight.159751. JCI Insight. 2022. PMID: 36345939 Free PMC article.
245 results