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Page 1
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients.
Venken K, Jacques P, Mortier C, Labadia ME, Decruy T, Coudenys J, Hoyt K, Wayne AL, Hughes R, Turner M, Van Gassen S, Martens L, Smith D, Harcken C, Wahle J, Wang CT, Verheugen E, Schryvers N, Varkas G, Cypers H, Wittoek R, Piette Y, Gyselbrecht L, Van Calenbergh S, Van den Bosch F, Saeys Y, Nabozny G, Elewaut D. Venken K, et al. Among authors: decruy t. Nat Commun. 2019 Jan 2;10(1):9. doi: 10.1038/s41467-018-07911-6. Nat Commun. 2019. PMID: 30602780 Free PMC article.
Synthesis and in vitro evaluation of alpha-GalCer epimers.
Trappeniers M, Goormans S, Van Beneden K, Decruy T, Linclau B, Al-Shamkhani A, Elliott T, Ottensmeier C, Werner JM, Elewaut D, Van Calenbergh S. Trappeniers M, et al. Among authors: decruy t. ChemMedChem. 2008 Jul;3(7):1061-70. doi: 10.1002/cmdc.200800021. ChemMedChem. 2008. PMID: 18418814
Synthesis and in vivo evaluation of 4-deoxy-4,4-difluoro-KRN7000.
Leung L, Tomassi C, Van Beneden K, Decruy T, Elewaut D, Elliott T, Al-Shamkhani A, Ottensmeier C, Van Calenbergh S, Werner J, Williams T, Linclau B. Leung L, et al. Among authors: decruy t. Org Lett. 2008 Oct 16;10(20):4433-6. doi: 10.1021/ol801663m. Epub 2008 Sep 18. Org Lett. 2008. PMID: 18798635
A multiparameter approach to monitor disease activity in collagen-induced arthritis.
Seeuws S, Jacques P, Van Praet J, Drennan M, Coudenys J, Decruy T, Deschepper E, Lepescheux L, Pujuguet P, Oste L, Vandeghinste N, Brys R, Verbruggen G, Elewaut D. Seeuws S, et al. Among authors: decruy t. Arthritis Res Ther. 2010;12(4):R160. doi: 10.1186/ar3119. Epub 2010 Aug 23. Arthritis Res Ther. 2010. PMID: 20731827 Free PMC article.
A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis.
Venken K, Seeuws S, Zabeau L, Jacques P, Decruy T, Coudenys J, Verheugen E, Windels F, Catteeuw D, Drennan M, Van Calenbergh S, Lambrecht BN, Yoshimura A, Tavernier J, Elewaut D. Venken K, et al. Among authors: decruy t. J Hepatol. 2014 Jan;60(1):175-82. doi: 10.1016/j.jhep.2013.08.008. Epub 2013 Aug 20. J Hepatol. 2014. PMID: 23973929
23 results