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5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.
Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, Wong AH, Blencowe BJ, Wang SC, Kapranov P, Kustra R, Labrie V, Klimasauskas S, Petronis A. Khare T, et al. Among authors: koncevicius k. Nat Struct Mol Biol. 2012 Oct;19(10):1037-43. doi: 10.1038/nsmb.2372. Epub 2012 Sep 9. Nat Struct Mol Biol. 2012. PMID: 22961382 Free PMC article.
DNA unmethylome profiling by covalent capture of CpG sites.
Kriukienė E, Labrie V, Khare T, Urbanavičiūtė G, Lapinaitė A, Koncevičius K, Li D, Wang T, Pai S, Ptak C, Gordevičius J, Wang SC, Petronis A, Klimašauskas S. Kriukienė E, et al. Among authors: koncevicius k. Nat Commun. 2013;4:2190. doi: 10.1038/ncomms3190. Nat Commun. 2013. PMID: 23877302 Free article.
Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging.
Labrie V, Buske OJ, Oh E, Jeremian R, Ptak C, Gasiūnas G, Maleckas A, Petereit R, Žvirbliene A, Adamonis K, Kriukienė E, Koncevičius K, Gordevičius J, Nair A, Zhang A, Ebrahimi S, Oh G, Šikšnys V, Kupčinskas L, Brudno M, Petronis A. Labrie V, et al. Among authors: koncevicius k. Nat Struct Mol Biol. 2016 Jun;23(6):566-73. doi: 10.1038/nsmb.3227. Epub 2016 May 9. Nat Struct Mol Biol. 2016. PMID: 27159559 Free PMC article.
Epigenetic age oscillates during the day.
Koncevičius K, Nair A, Šveikauskaitė A, Šeštokaitė A, Kazlauskaitė A, Dulskas A, Petronis A. Koncevičius K, et al. Aging Cell. 2024 Jul;23(7):e14170. doi: 10.1111/acel.14170. Epub 2024 Apr 18. Aging Cell. 2024. PMID: 38638005 Free PMC article.