Li J - Search Results

1

Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors.

Yu J, Liu J, Li D, Xu L, Hong D, Chang S, Xu L, Li J, Liu T, Zhou Y. Yu J, et al. Among authors: li d, li j. Eur J Med Chem. 2019 Feb 15;164:423-439. doi: 10.1016/j.ejmech.2018.12.072. Epub 2018 Dec 31. Eur J Med Chem. 2019. PMID: 30611983

2

A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway.

Pang T, Wang YJ, Gao YX, Xu Y, Li Q, Zhou YB, Xu L, Huang ZJ, Liao H, Zhang LY, Gao JR, Ye Q, Li J. Pang T, et al. Among authors: li j, li q. Acta Pharmacol Sin. 2016 Jun;37(6):741-52. doi: 10.1038/aps.2016.3. Epub 2016 Apr 25. Acta Pharmacol Sin. 2016. PMID: 27108601 Free PMC article.

3

Novel CHOP activator LGH00168 induces necroptosis in A549 human lung cancer cells via ROS-mediated ER stress and NF-κB inhibition.

Ma YM, Peng YM, Zhu QH, Gao AH, Chao B, He QJ, Li J, Hu YH, Zhou YB. Ma YM, et al. Among authors: li j. Acta Pharmacol Sin. 2016 Sep;37(10):1381-1390. doi: 10.1038/aps.2016.61. Epub 2016 Jun 6. Acta Pharmacol Sin. 2016. PMID: 27264312 Free PMC article.

4

Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface.

Ren J, Xu W, Tang L, Su M, Chen D, Chen YL, Zang Y, Li J, Shen J, Zhou Y, Xiong B. Ren J, et al. Among authors: li j. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4472-4476. doi: 10.1016/j.bmcl.2016.07.074. Epub 2016 Aug 2. Bioorg Med Chem Lett. 2016. PMID: 27528435

5

Cephalotanins A-D, Four Norditerpenoids Represent Three Highly Rigid Carbon Skeletons from Cephalotaxus sinensis.

Xu JB, Fan YY, Gan LS, Zhou YB, Li J, Yue JM. Xu JB, et al. Among authors: li j. Chemistry. 2016 Oct 4;22(41):14648-54. doi: 10.1002/chem.201603373. Epub 2016 Aug 19. Chemistry. 2016. PMID: 27539922

6

Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors.

Zhang J, Gao L, Xi J, Sheng L, Zhao Y, Xu L, Shao Y, Liu S, Zhuang R, Zhou Y, Li J. Zhang J, et al. Among authors: li j. Bioorg Med Chem. 2016 Dec 1;24(23):6206-6214. doi: 10.1016/j.bmc.2016.10.002. Epub 2016 Oct 6. Bioorg Med Chem. 2016. PMID: 27765408

7

Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors.

Zhuang R, Gao L, Lv X, Xi J, Sheng L, Zhao Y, He R, Hu X, Shao Y, Pan X, Liu S, Huang W, Zhou Y, Li J, Zhang J. Zhuang R, et al. Among authors: li j. Eur J Med Chem. 2017 Jan 27;126:1056-1070. doi: 10.1016/j.ejmech.2016.12.034. Epub 2016 Dec 18. Eur J Med Chem. 2017. PMID: 28027531

8

Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction.

Dong S, Lei Y, Jia S, Gao L, Li J, Zhu T, Liu S, Hu W. Dong S, et al. Among authors: li j. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1105-1108. doi: 10.1016/j.bmcl.2016.11.055. Epub 2016 Nov 22. Bioorg Med Chem Lett. 2017. PMID: 28111140

9

Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors.

Wang J, Su M, Li T, Gao A, Yang W, Sheng L, Zang Y, Li J, Liu H. Wang J, et al. Among authors: li t, li j. Eur J Med Chem. 2017 Mar 10;128:293-299. doi: 10.1016/j.ejmech.2017.01.035. Epub 2017 Jan 23. Eur J Med Chem. 2017. PMID: 28213282

10

Discovery of benzofuran-3(2H)-one derivatives as novel DRAK2 inhibitors that protect islet β-cells from apoptosis.

Wang S, Xu L, Lu YT, Liu YF, Han B, Liu T, Tang J, Li J, Wu J, Li JY, Yu LF, Yang F. Wang S, et al. Among authors: li jy, li j. Eur J Med Chem. 2017 Apr 21;130:195-208. doi: 10.1016/j.ejmech.2017.02.048. Epub 2017 Feb 21. Eur J Med Chem. 2017. PMID: 28249207

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