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Page 1
IDH3α regulates one-carbon metabolism in glioblastoma.
May JL, Kouri FM, Hurley LA, Liu J, Tommasini-Ghelfi S, Ji Y, Gao P, Calvert AE, Lee A, Chandel NS, Davuluri RV, Horbinski CM, Locasale JW, Stegh AH. May JL, et al. Among authors: chandel ns. Sci Adv. 2019 Jan 2;5(1):eaat0456. doi: 10.1126/sciadv.aat0456. eCollection 2019 Jan. Sci Adv. 2019. PMID: 30613765 Free PMC article.
HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.
Queisser MA, Dada LA, Deiss-Yehiely N, Angulo M, Zhou G, Kouri FM, Knab LM, Liu J, Stegh AH, DeCamp MM, Budinger GR, Chandel NS, Ciechanover A, Iwai K, Sznajder JI. Queisser MA, et al. Among authors: chandel ns. Am J Respir Crit Care Med. 2014 Sep 15;190(6):688-98. doi: 10.1164/rccm.201403-0463OC. Am J Respir Crit Care Med. 2014. PMID: 25118570 Free PMC article.
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, Zheng H, James CD, Burant CF, Chandel NS, Davuluri RV, Horbinski C, Stegh AH. Calvert AE, et al. Among authors: chandel ns. Cell Rep. 2017 May 30;19(9):1858-1873. doi: 10.1016/j.celrep.2017.05.014. Cell Rep. 2017. PMID: 28564604 Free PMC article.
Hexokinase 2 is dispensable for T cell-dependent immunity.
Mehta MM, Weinberg SE, Steinert EM, Chhiba K, Martinez CA, Gao P, Perlman HR, Bryce P, Hay N, Chandel NS. Mehta MM, et al. Among authors: chandel ns. Cancer Metab. 2018 Aug 17;6:10. doi: 10.1186/s40170-018-0184-5. eCollection 2018. Cancer Metab. 2018. PMID: 30140438 Free PMC article.
Mitochondrial complex III is essential for suppressive function of regulatory T cells.
Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS. Weinberg SE, et al. Among authors: chandel ns. Nature. 2019 Jan;565(7740):495-499. doi: 10.1038/s41586-018-0846-z. Epub 2019 Jan 9. Nature. 2019. PMID: 30626970 Free PMC article.
Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Martínez-Reyes I, Cardona LR, Kong H, Vasan K, McElroy GS, Werner M, Kihshen H, Reczek CR, Weinberg SE, Gao P, Steinert EM, Piseaux R, Budinger GRS, Chandel NS. Martínez-Reyes I, et al. Among authors: chandel ns. Nature. 2020 Sep;585(7824):288-292. doi: 10.1038/s41586-020-2475-6. Epub 2020 Jul 8. Nature. 2020. PMID: 32641834 Free PMC article.
Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma.
Miska J, Rashidi A, Lee-Chang C, Gao P, Lopez-Rosas A, Zhang P, Burga R, Castro B, Xiao T, Han Y, Hou D, Sampat S, Cordero A, Stoolman JS, Horbinski CM, Burns M, Reshetnyak YK, Chandel NS, Lesniak MS. Miska J, et al. Among authors: chandel ns. Sci Adv. 2021 Feb 17;7(8):eabc8929. doi: 10.1126/sciadv.abc8929. Print 2021 Feb. Sci Adv. 2021. PMID: 33597238 Free PMC article.
330 results