Auriola S - Search Results

1

L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery.

Puris E, Gynther M, Huttunen J, Auriola S, Huttunen KM. Puris E, et al. Among authors: auriola s. Eur J Pharm Sci. 2019 Mar 1;129:99-109. doi: 10.1016/j.ejps.2019.01.002. Epub 2019 Jan 6. Eur J Pharm Sci. 2019. PMID: 30625368

2

Uptake of free, calcium-bound and liposomal encapsulated nitrogen containing bisphosphonates by breast cancer cells.

Zlatev HP, Auriola S, Mönkkönen J, Määttä JA. Zlatev HP, et al. Among authors: auriola s. Eur J Pharm Sci. 2016 Apr 30;86:58-66. doi: 10.1016/j.ejps.2016.02.016. Epub 2016 Mar 5. Eur J Pharm Sci. 2016. PMID: 26957415

3

Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist.

Gynther M, Proietti Silvestri I, Hansen JC, Hansen KB, Malm T, Ishchenko Y, Larsen Y, Han L, Kayser S, Auriola S, Petsalo A, Nielsen B, Pickering DS, Bunch L. Gynther M, et al. Among authors: auriola s. J Med Chem. 2017 Dec 14;60(23):9885-9904. doi: 10.1021/acs.jmedchem.7b01624. Epub 2017 Dec 5. J Med Chem. 2017. PMID: 29205034 Free PMC article.

4

Structural properties for selective and efficient l-type amino acid transporter 1 (LAT1) mediated cellular uptake.

Kärkkäinen J, Gynther M, Kokkola T, Petsalo A, Auriola S, Lahtela-Kakkonen M, Laine K, Rautio J, Huttunen KM. Kärkkäinen J, et al. Among authors: auriola s. Int J Pharm. 2018 Jun 10;544(1):91-99. doi: 10.1016/j.ijpharm.2018.04.025. Epub 2018 Apr 15. Int J Pharm. 2018. PMID: 29669256

5

Alzheimer's Disease Phenotype or Inflammatory Insult Does Not Alter Function of L-Type Amino Acid Transporter 1 in Mouse Blood-Brain Barrier and Primary Astrocytes.

Gynther M, Puris E, Peltokangas S, Auriola S, Kanninen KM, Koistinaho J, Huttunen KM, Ruponen M, Vellonen KS. Gynther M, et al. Among authors: auriola s. Pharm Res. 2018 Nov 28;36(1):17. doi: 10.1007/s11095-018-2546-7. Pharm Res. 2018. PMID: 30488131 Free PMC article.

6

Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets.

Puris E, Gynther M, de Lange ECM, Auriola S, Hammarlund-Udenaes M, Huttunen KM, Loryan I. Puris E, et al. Among authors: auriola s. Mol Pharm. 2019 Jul 1;16(7):3261-3274. doi: 10.1021/acs.molpharmaceut.9b00502. Epub 2019 Jun 18. Mol Pharm. 2019. PMID: 31180686

7

L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia.

Huttunen J, Peltokangas S, Gynther M, Natunen T, Hiltunen M, Auriola S, Ruponen M, Vellonen KS, Huttunen KM. Huttunen J, et al. Among authors: auriola s. Sci Rep. 2019 Sep 6;9(1):12860. doi: 10.1038/s41598-019-49009-z. Sci Rep. 2019. PMID: 31492955 Free PMC article.

8

L-Type amino acid transporter 1 as a target for drug delivery.

Puris E, Gynther M, Auriola S, Huttunen KM. Puris E, et al. Among authors: auriola s. Pharm Res. 2020 May 6;37(5):88. doi: 10.1007/s11095-020-02826-8. Pharm Res. 2020. PMID: 32377929 Free PMC article. Review.

9

L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells.

Montaser AB, Järvinen J, Löffler S, Huttunen J, Auriola S, Lehtonen M, Jalkanen A, Huttunen KM. Montaser AB, et al. Among authors: auriola s. ACS Chem Neurosci. 2020 Dec 16;11(24):4301-4315. doi: 10.1021/acschemneuro.0c00564. Epub 2020 Nov 23. ACS Chem Neurosci. 2020. PMID: 33228353

10

Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP).

Markowicz-Piasecka M, Huttunen J, Montaser A, Adla SK, Auriola S, Lehtonen M, Huttunen KM. Markowicz-Piasecka M, et al. Among authors: auriola s. Int J Mol Sci. 2021 Jul 20;22(14):7727. doi: 10.3390/ijms22147727. Int J Mol Sci. 2021. PMID: 34299347 Free PMC article.

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