Cashman NR - Search Results

1

CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)^G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1.

Silverman JM, Christy D, Shyu CC, Moon KM, Fernando S, Gidden Z, Cowan CM, Ban Y, Stacey RG, Grad LI, McAlary L, Mackenzie IR, Foster LJ, Cashman NR. Silverman JM, et al. Among authors: cashman nr. J Biol Chem. 2019 Mar 8;294(10):3744-3759. doi: 10.1074/jbc.RA118.004825. Epub 2019 Jan 11. J Biol Chem. 2019. PMID: 30635404 Free PMC article.

2

Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis.

Rakhit R, Cunningham P, Furtos-Matei A, Dahan S, Qi XF, Crow JP, Cashman NR, Kondejewski LH, Chakrabartty A. Rakhit R, et al. Among authors: cashman nr. J Biol Chem. 2002 Dec 6;277(49):47551-6. doi: 10.1074/jbc.M207356200. Epub 2002 Sep 27. J Biol Chem. 2002. PMID: 12356748 Free article.

3

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

Rakhit R, Crow JP, Lepock JR, Kondejewski LH, Cashman NR, Chakrabartty A. Rakhit R, et al. Among authors: cashman nr. J Biol Chem. 2004 Apr 9;279(15):15499-504. doi: 10.1074/jbc.M313295200. Epub 2004 Jan 20. J Biol Chem. 2004. PMID: 14734542 Free article.

4

Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS).

Cashman N, Tan LY, Krieger C, Mädler B, Mackay A, Mackenzie I, Benny B, Nantel S, Fabros M, Shinobu L, Yousefi M, Eisen A. Cashman N, et al. Muscle Nerve. 2008 May;37(5):620-5. doi: 10.1002/mus.20951. Muscle Nerve. 2008. PMID: 18335482 Clinical Trial.

5

Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis.

Rademakers R, Stewart H, Dejesus-Hernandez M, Krieger C, Graff-Radford N, Fabros M, Briemberg H, Cashman N, Eisen A, Mackenzie IR. Rademakers R, et al. Muscle Nerve. 2010 Aug;42(2):170-6. doi: 10.1002/mus.21665. Muscle Nerve. 2010. PMID: 20544928 Free PMC article.

6

Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide.

Taghibiglou C, Lu J, Mackenzie IR, Wang YT, Cashman NR. Taghibiglou C, et al. Among authors: cashman nr. Biochem Biophys Res Commun. 2011 Sep 23;413(2):159-63. doi: 10.1016/j.bbrc.2011.08.011. Epub 2011 Aug 19. Biochem Biophys Res Commun. 2011. PMID: 21871872

7

Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.

Grad LI, Guest WC, Yanai A, Pokrishevsky E, O'Neill MA, Gibbs E, Semenchenko V, Yousefi M, Wishart DS, Plotkin SS, Cashman NR. Grad LI, et al. Among authors: cashman nr. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16398-403. doi: 10.1073/pnas.1102645108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930926 Free PMC article.

8

Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit.

Guest WC, Silverman JM, Pokrishevsky E, O'Neill MA, Grad LI, Cashman NR. Guest WC, et al. Among authors: cashman nr. J Toxicol Environ Health A. 2011;74(22-24):1433-59. doi: 10.1080/15287394.2011.618967. J Toxicol Environ Health A. 2011. PMID: 22043906 Review.

9

Clinical and pathological features of amyotrophic lateral sclerosis caused by mutation in the C9ORF72 gene on chromosome 9p.

Stewart H, Rutherford NJ, Briemberg H, Krieger C, Cashman N, Fabros M, Baker M, Fok A, DeJesus-Hernandez M, Eisen A, Rademakers R, Mackenzie IR. Stewart H, et al. Acta Neuropathol. 2012 Mar;123(3):409-17. doi: 10.1007/s00401-011-0937-5. Epub 2012 Jan 7. Acta Neuropathol. 2012. PMID: 22228244 Free PMC article.

10

Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.

Pokrishevsky E, Grad LI, Yousefi M, Wang J, Mackenzie IR, Cashman NR. Pokrishevsky E, et al. Among authors: cashman nr. PLoS One. 2012;7(4):e35050. doi: 10.1371/journal.pone.0035050. Epub 2012 Apr 6. PLoS One. 2012. PMID: 22493728 Free PMC article.

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