Shiau CW - Search Results

1

Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression.

Liu CY, Huang TT, Chen YT, Chen JL, Chu PY, Huang CT, Wang WL, Lau KY, Dai MS, Shiau CW, Tseng LM. Liu CY, et al. Among authors: shiau cw. EBioMedicine. 2019 Feb;40:263-275. doi: 10.1016/j.ebiom.2018.12.032. Epub 2019 Jan 14. EBioMedicine. 2019. PMID: 30651219 Free PMC article.

2

Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.

Tai WT, Cheng AL, Shiau CW, Liu CY, Ko CH, Lin MW, Chen PJ, Chen KF. Tai WT, et al. Among authors: shiau cw. Mol Cancer Ther. 2012 Feb;11(2):452-63. doi: 10.1158/1535-7163.MCT-11-0412. Epub 2011 Dec 16. Mol Cancer Ther. 2012. PMID: 22180308

3

A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation.

Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW. Chen KF, et al. Among authors: shiau cw. Cancer Lett. 2012 Aug 1;321(1):27-35. doi: 10.1016/j.canlet.2012.03.023. Epub 2012 Mar 28. Cancer Lett. 2012. PMID: 22465052

4

CIP2A is a target of bortezomib in human triple negative breast cancer cells.

Tseng LM, Liu CY, Chang KC, Chu PY, Shiau CW, Chen KF. Tseng LM, et al. Among authors: shiau cw. Breast Cancer Res. 2012 Apr 26;14(2):R68. doi: 10.1186/bcr3175. Breast Cancer Res. 2012. PMID: 22537901 Free PMC article.

5

Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells.

Chen KF, Lin JP, Shiau CW, Tai WT, Liu CY, Yu HC, Chen PJ, Cheng AL. Chen KF, et al. Among authors: shiau cw. Biochem Pharmacol. 2012 Aug 1;84(3):268-77. doi: 10.1016/j.bcp.2012.04.023. Epub 2012 May 9. Biochem Pharmacol. 2012. PMID: 22580047

6

Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity.

Chen KF, Tai WT, Hsu CY, Huang JW, Liu CY, Chen PJ, Kim I, Shiau CW. Chen KF, et al. Among authors: shiau cw. Eur J Med Chem. 2012 Sep;55:220-7. doi: 10.1016/j.ejmech.2012.07.023. Epub 2012 Jul 23. Eur J Med Chem. 2012. PMID: 22871485

7

SC-1, a sorafenib derivative, shows anti-tumor effects in osteogenic sarcoma cells.

Wang CT, Lin CS, Shiau CW, Chu PY, Hsiao CC, Chiang YL, Tai WT, Chen KF. Wang CT, et al. Among authors: shiau cw. J Orthop Res. 2013 Feb;31(2):335-42. doi: 10.1002/jor.22218. Epub 2012 Aug 23. J Orthop Res. 2013. PMID: 22926753 Free article.

8

Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody.

Chen KF, Chen HL, Shiau CW, Liu CY, Chu PY, Tai WT, Ichikawa K, Chen PJ, Cheng AL. Chen KF, et al. Among authors: shiau cw. Br J Pharmacol. 2013 Feb;168(3):658-72. doi: 10.1111/j.1476-5381.2012.02212.x. Br J Pharmacol. 2013. PMID: 22978563 Free PMC article.

9

Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity.

Chen KF, Pao KC, Su JC, Chou YC, Liu CY, Chen HJ, Huang JW, Kim I, Shiau CW. Chen KF, et al. Among authors: shiau cw. Bioorg Med Chem. 2012 Oct 15;20(20):6144-53. doi: 10.1016/j.bmc.2012.08.039. Epub 2012 Aug 30. Bioorg Med Chem. 2012. PMID: 22980218

10

Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists.

Su JC, Chen KF, Chen WL, Liu CY, Huang JW, Tai WT, Chen PJ, Kim I, Shiau CW. Su JC, et al. Among authors: shiau cw. Eur J Med Chem. 2012 Oct;56:127-33. doi: 10.1016/j.ejmech.2012.08.024. Epub 2012 Aug 27. Eur J Med Chem. 2012. PMID: 22982119

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