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Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clusters as a response pattern to lenalidomide.
Mährle T, Akyüz N, Fuchs P, Bonzanni N, Simnica D, Germing U, Asemissen AM, Jann JC, Nolte F, Hofmann WK, Nowak D, Binder M. Mährle T, et al. Among authors: hofmann wk. Haematologica. 2019 Jul;104(7):1355-1364. doi: 10.3324/haematol.2018.208223. Epub 2019 Jan 17. Haematologica. 2019. PMID: 30655375 Free PMC article. Clinical Trial.
Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy.
Nowak D, Le Toriellec E, Stern MH, Kawamata N, Akagi T, Dyer MJ, Hofmann WK, Ogawa S, Koeffler HP. Nowak D, et al. Among authors: hofmann wk. Haematologica. 2009 Apr;94(4):518-27. doi: 10.3324/haematol.2008.001347. Epub 2009 Mar 10. Haematologica. 2009. PMID: 19278963 Free PMC article.
Detection of differential mitotic cell age in bone marrow CD34(+) cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature.
Mossner M, Hopfer O, Nowak D, Baldus CD, Neumann U, Kmetsch A, Benlasfer O, John T, Perka C, Thiel E, Hofmann WK. Mossner M, et al. Among authors: hofmann wk. Exp Hematol. 2010 Aug;38(8):661-5. doi: 10.1016/j.exphem.2010.03.022. Epub 2010 Jun 16. Exp Hematol. 2010. PMID: 20399247
Genome-wide Mapping of Copy Number Variations Using SNP Arrays.
Nowak D, Hofmann WK, Koeffler HP. Nowak D, et al. Among authors: hofmann wk. Transfus Med Hemother. 2009;36(4):246-251. doi: 10.1159/000225372. Epub 2009 Jul 10. Transfus Med Hemother. 2009. PMID: 21049075 Free PMC article.
Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts.
Blau O, Baldus CD, Hofmann WK, Thiel G, Nolte F, Burmeister T, Türkmen S, Benlasfer O, Schümann E, Sindram A, Molkentin M, Mundlos S, Keilholz U, Thiel E, Blau IW. Blau O, et al. Among authors: hofmann wk. Blood. 2011 Nov 17;118(20):5583-92. doi: 10.1182/blood-2011-03-343467. Epub 2011 Sep 23. Blood. 2011. PMID: 21948175 Free PMC article.
397 results