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How to design a dose-finding study using the continual reassessment method.
Wheeler GM, Mander AP, Bedding A, Brock K, Cornelius V, Grieve AP, Jaki T, Love SB, Odondi L, Weir CJ, Yap C, Bond SJ. Wheeler GM, et al. Among authors: yap c. BMC Med Res Methodol. 2019 Jan 18;19(1):18. doi: 10.1186/s12874-018-0638-z. BMC Med Res Methodol. 2019. PMID: 30658575 Free PMC article.
Embracing model-based designs for dose-finding trials.
Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V. Love SB, et al. Among authors: yap c. Br J Cancer. 2017 Jul 25;117(3):332-339. doi: 10.1038/bjc.2017.186. Epub 2017 Jun 29. Br J Cancer. 2017. PMID: 28664918 Free PMC article. Review.
Implementing the EffTox dose-finding design in the Matchpoint trial.
Brock K, Billingham L, Copland M, Siddique S, Sirovica M, Yap C. Brock K, et al. Among authors: yap c. BMC Med Res Methodol. 2017 Jul 20;17(1):112. doi: 10.1186/s12874-017-0381-x. BMC Med Res Methodol. 2017. PMID: 28728594 Free PMC article. Clinical Trial.
Adaptive designs in clinical trials: why use them, and how to run and report them.
Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T. Pallmann P, et al. Among authors: yap c. BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7. BMC Med. 2018. PMID: 29490655 Free PMC article.
Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia.
Craddock C, Slade D, De Santo C, Wheat R, Ferguson P, Hodgkinson A, Brock K, Cavenagh J, Ingram W, Dennis M, Malladi R, Siddique S, Mussai F, Yap C. Craddock C, et al. Among authors: yap c. J Clin Oncol. 2019 Mar 1;37(7):580-588. doi: 10.1200/JCO.18.00889. Epub 2019 Jan 17. J Clin Oncol. 2019. PMID: 30653424 Free PMC article. Clinical Trial.
Adaptive trial designs: what is the continual reassessment method?
Millen GC, Yap C. Millen GC, et al. Among authors: yap c. Arch Dis Child Educ Pract Ed. 2021 Jun;106(3):175-177. doi: 10.1136/archdischild-2019-316931. Epub 2019 Oct 30. Arch Dis Child Educ Pract Ed. 2021. PMID: 31666290 No abstract available.
832 results