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SIRT3 regulates progression and development of diseases of aging.
McDonnell E, Peterson BS, Bomze HM, Hirschey MD. McDonnell E, et al. Among authors: hirschey md. Trends Endocrinol Metab. 2015 Sep;26(9):486-492. doi: 10.1016/j.tem.2015.06.001. Epub 2015 Jun 29. Trends Endocrinol Metab. 2015. PMID: 26138757 Free PMC article. Review.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y. Tan M, et al. Among authors: hirschey md. Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014. Cell Metab. 2014. PMID: 24703693 Free PMC article.
SnapShot: Mammalian Sirtuins.
Anderson KA, Green MF, Huynh FK, Wagner GR, Hirschey MD. Anderson KA, et al. Among authors: hirschey md. Cell. 2014 Nov 6;159(4):956-956.e1. doi: 10.1016/j.cell.2014.10.045. Cell. 2014. PMID: 25417168 Free PMC article.
90 results