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A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.
Song Y, Rongvaux A, Taylor A, Jiang T, Tebaldi T, Balasubramanian K, Bagale A, Terzi YK, Gbyli R, Wang X, Fu X, Gao Y, Zhao J, Podoltsev N, Xu M, Neparidze N, Wong E, Torres R, Bruscia EM, Kluger Y, Manz MG, Flavell RA, Halene S. Song Y, et al. Among authors: bruscia em. Nat Commun. 2019 Jan 21;10(1):366. doi: 10.1038/s41467-018-08166-x. Nat Commun. 2019. PMID: 30664659 Free PMC article.
SRF is required for neutrophil migration in response to inflammation.
Taylor A, Tang W, Bruscia EM, Zhang PX, Lin A, Gaines P, Wu D, Halene S. Taylor A, et al. Among authors: bruscia em. Blood. 2014 May 8;123(19):3027-36. doi: 10.1182/blood-2013-06-507582. Epub 2014 Feb 26. Blood. 2014. PMID: 24574460 Free PMC article.
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.
Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA. Song Y, et al. Among authors: bruscia em. Science. 2021 Mar 5;371(6533):1019-1025. doi: 10.1126/science.abe2485. Science. 2021. PMID: 33674488 Free PMC article.
Human neutrophil development and functionality are enabled in a humanized mouse model.
Zheng Y, Sefik E, Astle J, Karatepe K, Öz HH, Solis AG, Jackson R, Luo HR, Bruscia EM, Halene S, Shan L, Flavell RA. Zheng Y, et al. Among authors: bruscia em. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2121077119. doi: 10.1073/pnas.2121077119. Epub 2022 Oct 21. Proc Natl Acad Sci U S A. 2022. PMID: 36269862 Free PMC article.
Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.
Öz HH, Cheng EC, Di Pietro C, Tebaldi T, Biancon G, Zeiss C, Zhang PX, Huang PH, Esquibies SS, Britto CJ, Schupp JC, Murray TS, Halene S, Krause DS, Egan ME, Bruscia EM. Öz HH, et al. Among authors: bruscia em. Cell Rep. 2022 Dec 13;41(11):111797. doi: 10.1016/j.celrep.2022.111797. Cell Rep. 2022. PMID: 36516754 Free PMC article.
Plasticity of bone marrow-derived stem cells.
Grove JE, Bruscia E, Krause DS. Grove JE, et al. Stem Cells. 2004;22(4):487-500. doi: 10.1634/stemcells.22-4-487. Stem Cells. 2004. PMID: 15277695 Review.
Engraftment of bone marrow-derived epithelial cells.
Van Arnam JS, Herzog E, Grove J, Bruscia E, Ziegler E, Swenson S, Krause DS. Van Arnam JS, et al. Stem Cell Rev. 2005;1(1):21-7. doi: 10.1385/SCR:1:1:021. Stem Cell Rev. 2005. PMID: 17132871 Review.
48 results