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Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8+ T cell antitumor immunity.
Li A, Chang Y, Song NJ, Wu X, Chung D, Riesenberg BP, Velegraki M, Giuliani GD, Das K, Okimoto T, Kwon H, Chakravarthy KB, Bolyard C, Wang Y, He K, Gatti-Mays M, Das J, Yang Y, Gewirth DT, Ma Q, Carbone D, Li Z. Li A, et al. Among authors: riesenberg bp. J Immunother Cancer. 2022 Sep;10(9):e005433. doi: 10.1136/jitc-2022-005433. J Immunother Cancer. 2022. PMID: 36096533 Free PMC article.
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β.
Metelli A, Wu BX, Riesenberg B, Guglietta S, Huck JD, Mills C, Li A, Rachidi S, Krieg C, Rubinstein MP, Gewirth DT, Sun S, Lilly MB, Wahlquist AH, Carbone DP, Yang Y, Liu B, Li Z. Metelli A, et al. Among authors: riesenberg b. Sci Transl Med. 2020 Jan 8;12(525):eaay4860. doi: 10.1126/scitranslmed.aay4860. Sci Transl Med. 2020. PMID: 31915300 Free PMC article.
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.
Ansa-Addo EA, Thaxton J, Hong F, Wu BX, Zhang Y, Fugle CW, Metelli A, Riesenberg B, Williams K, Gewirth DT, Chiosis G, Liu B, Li Z. Ansa-Addo EA, et al. Among authors: riesenberg b. Curr Top Med Chem. 2016;16(25):2765-78. doi: 10.2174/1568026616666160413141613. Curr Top Med Chem. 2016. PMID: 27072698 Free PMC article. Review.
Platelets subvert T cell immunity against cancer via GARP-TGFβ axis.
Rachidi S, Metelli A, Riesenberg B, Wu BX, Nelson MH, Wallace C, Paulos CM, Rubinstein MP, Garrett-Mayer E, Hennig M, Bearden DW, Yang Y, Liu B, Li Z. Rachidi S, et al. Among authors: riesenberg b. Sci Immunol. 2017 May 5;2(11):eaai7911. doi: 10.1126/sciimmunol.aai7911. Sci Immunol. 2017. PMID: 28763790 Free PMC article.
Androgen conspires with the CD8+ T cell exhaustion program and contributes to sex bias in cancer.
Kwon H, Schafer JM, Song NJ, Kaneko S, Li A, Xiao T, Ma A, Allen C, Das K, Zhou L, Riesenberg B, Chang Y, Weltge P, Velegraki M, Oh DY, Fong L, Ma Q, Sundi D, Chung D, Li X, Li Z. Kwon H, et al. Among authors: riesenberg b. Sci Immunol. 2022 Jul;7(73):eabq2630. doi: 10.1126/sciimmunol.abq2630. Epub 2022 Jul 1. Sci Immunol. 2022. PMID: 35420889 Free PMC article.
20 results