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Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function.
Hurcombe JA, Hartley P, Lay AC, Ni L, Bedford JJ, Leader JP, Singh S, Murphy A, Scudamore CL, Marquez E, Barrington AF, Pinto V, Marchetti M, Wong LF, Uney J, Saleem MA, Mathieson PW, Patel S, Walker RJ, Woodgett JR, Quaggin SE, Welsh GI, Coward RJM. Hurcombe JA, et al. Among authors: marquez e. Nat Commun. 2019 Jan 24;10(1):403. doi: 10.1038/s41467-018-08235-1. Nat Commun. 2019. PMID: 30679422 Free PMC article.
IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes.
Santamaria B, Marquez E, Lay A, Carew RM, González-Rodríguez Á, Welsh GI, Ni L, Hale LJ, Ortiz A, Saleem MA, Brazil DP, Coward RJ, Valverde ÁM. Santamaria B, et al. Among authors: marquez e. Biochim Biophys Acta. 2015 Dec;1853(12):3224-34. doi: 10.1016/j.bbamcr.2015.09.020. Epub 2015 Sep 16. Biochim Biophys Acta. 2015. PMID: 26384875 Free article.
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.
Lay AC, Hale LJ, Stowell-Connolly H, Pope RJP, Nair V, Ju W, Marquez E, Rollason R, Hurcombe JA, Hayes B, Roberts T, Gillam L, Allington J, Nelson RG, Kretzler M, Holly JMP, Perks CM, McArdle CA, Welsh GI, Coward RJM. Lay AC, et al. Among authors: marquez e. Diabetologia. 2021 Jul;64(7):1690-1702. doi: 10.1007/s00125-021-05427-1. Epub 2021 Mar 24. Diabetologia. 2021. PMID: 33758952 Free PMC article.
Renin-angiotensin system within the diabetic podocyte.
Márquez E, Riera M, Pascual J, Soler MJ. Márquez E, et al. Am J Physiol Renal Physiol. 2015 Jan 1;308(1):F1-10. doi: 10.1152/ajprenal.00531.2013. Epub 2014 Oct 22. Am J Physiol Renal Physiol. 2015. PMID: 25339703 Free article. Review.
337 results