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A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Hajj Chehade M, Pelosi L, Fyfe CD, Loiseau L, Rascalou B, Brugière S, Kazemzadeh K, Vo CD, Ciccone L, Aussel L, Couté Y, Fontecave M, Barras F, Lombard M, Pierrel F. Hajj Chehade M, et al. Cell Chem Biol. 2019 Apr 18;26(4):482-492.e7. doi: 10.1016/j.chembiol.2018.12.001. Epub 2019 Jan 24. Cell Chem Biol. 2019. PMID: 30686758 Free article.
ubiI, a new gene in Escherichia coli coenzyme Q biosynthesis, is involved in aerobic C5-hydroxylation.
Hajj Chehade M, Loiseau L, Lombard M, Pecqueur L, Ismail A, Smadja M, Golinelli-Pimpaneau B, Mellot-Draznieks C, Hamelin O, Aussel L, Kieffer-Jaquinod S, Labessan N, Barras F, Fontecave M, Pierrel F. Hajj Chehade M, et al. J Biol Chem. 2013 Jul 5;288(27):20085-92. doi: 10.1074/jbc.M113.480368. Epub 2013 May 24. J Biol Chem. 2013. PMID: 23709220 Free PMC article.
Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site.
Rendon J, Pilet E, Fahs Z, Seduk F, Sylvi L, Hajj Chehade M, Pierrel F, Guigliarelli B, Magalon A, Grimaldi S. Rendon J, et al. Among authors: hajj chehade m. Biochim Biophys Acta. 2015 Aug;1847(8):739-47. doi: 10.1016/j.bbabio.2015.05.001. Epub 2015 May 12. Biochim Biophys Acta. 2015. PMID: 25976528 Free article.
The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ.
Loiseau L, Fyfe C, Aussel L, Hajj Chehade M, Hernández SB, Faivre B, Hamdane D, Mellot-Draznieks C, Rascalou B, Pelosi L, Velours C, Cornu D, Lombard M, Casadesús J, Pierrel F, Fontecave M, Barras F. Loiseau L, et al. Among authors: hajj chehade m. J Biol Chem. 2017 Jul 14;292(28):11937-11950. doi: 10.1074/jbc.M117.789164. Epub 2017 May 30. J Biol Chem. 2017. PMID: 28559279 Free PMC article.