Xiao Y - Search Results

1

Sortase-mediated fluorescent labeling of CRISPR complexes.

Dillard KE, Schaub JM, Brown MW, Saifuddin FA, Xiao Y, Hernandez E, Dahlhauser SD, Anslyn EV, Ke A, Finkelstein IJ. Dillard KE, et al. Among authors: xiao y. Methods Enzymol. 2019;616:43-59. doi: 10.1016/bs.mie.2018.10.031. Epub 2018 Dec 17. Methods Enzymol. 2019. PMID: 30691654 Free PMC article.

2

Massively Parallel Biophysical Analysis of CRISPR-Cas Complexes on Next Generation Sequencing Chips.

Jung C, Hawkins JA, Jones SK Jr, Xiao Y, Rybarski JR, Dillard KE, Hussmann J, Saifuddin FA, Savran CA, Ellington AD, Ke A, Press WH, Finkelstein IJ. Jung C, et al. Among authors: xiao y. Cell. 2017 Jun 29;170(1):35-47.e13. doi: 10.1016/j.cell.2017.05.044. Cell. 2017. PMID: 28666121 Free PMC article.

3

Assembly and Translocation of a CRISPR-Cas Primed Acquisition Complex.

Dillard KE, Brown MW, Johnson NV, Xiao Y, Dolan A, Hernandez E, Dahlhauser SD, Kim Y, Myler LR, Anslyn EV, Ke A, Finkelstein IJ. Dillard KE, et al. Among authors: xiao y. Cell. 2018 Nov 1;175(4):934-946.e15. doi: 10.1016/j.cell.2018.09.039. Epub 2018 Oct 18. Cell. 2018. PMID: 30343903 Free PMC article.

4

Reconstitution and biochemical characterization of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems.

Xiao Y, Ke A. Xiao Y, et al. Methods Enzymol. 2019;616:27-41. doi: 10.1016/bs.mie.2018.11.003. Epub 2018 Dec 17. Methods Enzymol. 2019. PMID: 30691647 Free PMC article.

5

How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.

Xiao Y, Ng S, Nam KH, Ke A. Xiao Y, et al. Nature. 2017 Oct 5;550(7674):137-141. doi: 10.1038/nature24020. Epub 2017 Sep 4. Nature. 2017. PMID: 28869593 Free PMC article.

6

Real-time observation of CRISPR spacer acquisition by Cas1-Cas2 integrase.

Budhathoki JB, Xiao Y, Schuler G, Hu C, Cheng A, Ding F, Ke A. Budhathoki JB, et al. Among authors: xiao y. Nat Struct Mol Biol. 2020 May;27(5):489-499. doi: 10.1038/s41594-020-0415-7. Epub 2020 May 4. Nat Struct Mol Biol. 2020. PMID: 32367067 Free PMC article.

7

Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas.

Dolan AE, Hou Z, Xiao Y, Gramelspacher MJ, Heo J, Howden SE, Freddolino PL, Ke A, Zhang Y. Dolan AE, et al. Among authors: xiao y. Mol Cell. 2019 Jun 6;74(5):936-950.e5. doi: 10.1016/j.molcel.2019.03.014. Epub 2019 Apr 8. Mol Cell. 2019. PMID: 30975459 Free PMC article.

8

Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems.

Tan R, Krueger RK, Gramelspacher MJ, Zhou X, Xiao Y, Ke A, Hou Z, Zhang Y. Tan R, et al. Among authors: xiao y. Mol Cell. 2022 Feb 17;82(4):852-867.e5. doi: 10.1016/j.molcel.2021.12.032. Epub 2022 Jan 19. Mol Cell. 2022. PMID: 35051351 Free PMC article.

9

PIWI Takes a Giant Step.

Xiao Y, Ke A. Xiao Y, et al. Cell. 2016 Oct 6;167(2):310-312. doi: 10.1016/j.cell.2016.09.043. Cell. 2016. PMID: 27716504 Free article.

10

Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.

Xiao Y, Luo M, Hayes RP, Kim J, Ng S, Ding F, Liao M, Ke A. Xiao Y, et al. Cell. 2017 Jun 29;170(1):48-60.e11. doi: 10.1016/j.cell.2017.06.012. Cell. 2017. PMID: 28666122 Free PMC article.

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