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The endogenous bioactive lipid prostaglandin D2-glycerol ester reduces murine colitis via DP1 and PPARγ receptors.
Alhouayek M, Buisseret B, Paquot A, Guillemot-Legris O, Muccioli GG. Alhouayek M, et al. Among authors: paquot a. FASEB J. 2018 Sep;32(9):5000-5011. doi: 10.1096/fj.201701205R. Epub 2018 Apr 9. FASEB J. 2018. PMID: 29630407
However, it also metabolizes the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide into the less well-studied bioactive lipids PG-glycerol esters (PG-Gs) and PG-ethanolamides (PG-EAs or prostamides). We previously showed that PGD(2)-G, a product of 2-AG oxygena …
However, it also metabolizes the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide into the less well-studied bioactive lipids P …
The origin of neural stem cells impacts their interactions with targeted-lipid nanocapsules: Potential role of plasma membrane lipid composition and fluidity.
Carradori D, Dos Santos AG, Masquelier J, Paquot A, Saulnier P, Eyer J, Préat V, Muccioli GG, Mingeot-Leclercq MP, des Rieux A. Carradori D, et al. Among authors: paquot a. J Control Release. 2018 Dec 28;292:248-255. doi: 10.1016/j.jconrel.2018.11.005. Epub 2018 Nov 5. J Control Release. 2018. PMID: 30408552
The α/β-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids.
Bottemanne P, Paquot A, Ameraoui H, Alhouayek M, Muccioli GG. Bottemanne P, et al. Among authors: paquot a. FASEB J. 2019 Jun;33(6):7635-7646. doi: 10.1096/fj.201802259R. Epub 2019 Mar 21. FASEB J. 2019. PMID: 30896979
Lung inflammation plays a crucial role in the pathogenesis of many respiratory diseases that are in need of new therapeutic strategies. ...Therefore, we thought to assess the effects of ABHD6 inhibition in a mouse model of acute lung injury (ALI) induced by intratra …
Lung inflammation plays a crucial role in the pathogenesis of many respiratory diseases that are in need of new therapeutic strategie …
Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis.
Pollet H, Cloos AS, Stommen A, Vanderroost J, Conrard L, Paquot A, Ghodsi M, Carquin M, Léonard C, Guthmann M, Lingurski M, Vermylen C, Killian T, Gatto L, Rider M, Pyr Dit Ruys S, Vertommen D, Vikkula M, Brouillard P, Van Der Smissen P, Muccioli GG, Tyteca D. Pollet H, et al. Among authors: paquot a. Biomolecules. 2020 Jul 29;10(8):1120. doi: 10.3390/biom10081120. Biomolecules. 2020. PMID: 32751168 Free PMC article.
37 results