Slape CI - Search Results

1

The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1.

Shields BJ, Slape CI, Vo N, Jackson JT, Pliego-Zamora A, Ranasinghe H, Shi W, Curtis DJ, McCormack MP. Shields BJ, et al. Among authors: slape ci. Leukemia. 2019 Aug;33(8):1868-1880. doi: 10.1038/s41375-018-0361-0. Epub 2019 Jan 30. Leukemia. 2019. PMID: 30700838

2

The fusion partner specifies the oncogenic potential of NUP98 fusion proteins.

Saw J, Curtis DJ, Hussey DJ, Dobrovic A, Aplan PD, Slape CI. Saw J, et al. Among authors: slape ci. Leuk Res. 2013 Dec;37(12):1668-73. doi: 10.1016/j.leukres.2013.09.013. Epub 2013 Sep 21. Leuk Res. 2013. PMID: 24090997 Free PMC article.

3

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome.

Slape CI, Saw J, Jowett JB, Aplan PD, Strasser A, Jane SM, Curtis DJ. Slape CI, et al. Blood. 2012 Sep 20;120(12):2475-83. doi: 10.1182/blood-2012-05-430736. Epub 2012 Jul 31. Blood. 2012. PMID: 22855610 Free PMC article.

4

Cell-Extrinsic Differentiation Block Mediated by EphA3 in Pre-Leukaemic Thymus Contributes to Disease Progression.

Pliego Zamora AC, Ranasinghe H, Lisle JE, Ng CK, Huang S, Wadlow R, Scott AM, Boyd AW, Slape CI. Pliego Zamora AC, et al. Among authors: slape ci. Cancers (Basel). 2021 Jul 31;13(15):3858. doi: 10.3390/cancers13153858. Cancers (Basel). 2021. PMID: 34359759 Free PMC article.

5

PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.

Guirguis AA, Slape CI, Failla LM, Saw J, Tremblay CS, Powell DR, Rossello F, Wei A, Strasser A, Curtis DJ. Guirguis AA, et al. Among authors: slape ci. Cell Death Differ. 2016 Jun;23(6):1049-59. doi: 10.1038/cdd.2015.159. Epub 2016 Jan 8. Cell Death Differ. 2016. PMID: 26742432 Free PMC article.

6

Mouse embryonic stem cells that express a NUP98-HOXD13 fusion protein are impaired in their ability to differentiate and can be complemented by BCR-ABL.

Slape C, Chung YJ, Soloway PD, Tessarollo L, Aplan PD. Slape C, et al. Leukemia. 2007 Jun;21(6):1239-48. doi: 10.1038/sj.leu.2404648. Epub 2007 Mar 22. Leukemia. 2007. PMID: 17377591 Free PMC article.

7

Seeking commonalities in fusion proteins of NUP98.

Slape CI. Slape CI. Nat Struct Mol Biol. 2021 Feb;28(2):123-124. doi: 10.1038/s41594-021-00558-w. Nat Struct Mol Biol. 2021. PMID: 33479543 No abstract available.

8

The role of NUP98 gene fusions in hematologic malignancy.

Slape C, Aplan PD. Slape C, et al. Leuk Lymphoma. 2004 Jul;45(7):1341-50. doi: 10.1080/10428190310001659325. Leuk Lymphoma. 2004. PMID: 15359631 Review.

9

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Greenblatt S, et al. Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8. Blood. 2012. PMID: 22323452 Free PMC article.

10

Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.

Slape C, Hartung H, Lin YW, Bies J, Wolff L, Aplan PD. Slape C, et al. Cancer Res. 2007 Jun 1;67(11):5148-55. doi: 10.1158/0008-5472.CAN-07-0075. Cancer Res. 2007. PMID: 17545593 Free PMC article.

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