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Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes.
Wan Y, Ceci L, Wu N, Zhou T, Chen L, Venter J, Francis H, Bernuzzi F, Invernizzi P, Kyritsi K, Baker P, Huang Q, Wu C, Sybenga A, Alpini G, Meng F, Glaser S. Wan Y, et al. Among authors: wu c, wu n. Lab Invest. 2019 Jun;99(6):764-776. doi: 10.1038/s41374-018-0178-5. Epub 2019 Jan 30. Lab Invest. 2019. PMID: 30700848 Free PMC article.
Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation.
Guo X, Shu C, Li H, Pei Y, Woo SL, Zheng J, Liu M, Xu H, Botchlett R, Guo T, Cai Y, Gao X, Zhou J, Chen L, Li Q, Xiao X, Xie L, Zhang KK, Ji JY, Huo Y, Meng F, Alpini G, Li P, Wu C. Guo X, et al. Among authors: wu c. Sci Rep. 2017 Jul 25;7(1):6355. doi: 10.1038/s41598-017-05884-y. Sci Rep. 2017. PMID: 28743914 Free PMC article.
Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury.
Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, Francis H, Kennedy L, Sato K, Zhou T, Kyritsi K, Huang Q, Annable T, Wu C, Glaser S, Alpini G, Meng F. Wan Y, et al. Among authors: wu c, wu n. Am J Pathol. 2017 Dec;187(12):2788-2798. doi: 10.1016/j.ajpath.2017.08.027. Epub 2017 Nov 8. Am J Pathol. 2017. PMID: 29128099 Free PMC article.
Knockout of microRNA-21 attenuates alcoholic hepatitis through the VHL/NF-κB signaling pathway in hepatic stellate cells.
Wu N, McDaniel K, Zhou T, Ramos-Lorenzo S, Wu C, Huang L, Chen D, Annable T, Francis H, Glaser S, Alpini G, Meng F. Wu N, et al. Among authors: wu c. Am J Physiol Gastrointest Liver Physiol. 2018 Sep 1;315(3):G385-G398. doi: 10.1152/ajpgi.00111.2018. Epub 2018 May 31. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29848019 Free PMC article.
Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.
Zhou T, Wu N, Meng F, Venter J, Giang TK, Francis H, Kyritsi K, Wu C, Franchitto A, Alvaro D, Marzioni M, Onori P, Mancinelli R, Gaudio E, Glaser S, Alpini G. Zhou T, et al. Among authors: wu c, wu n. Lab Invest. 2018 Nov;98(11):1449-1464. doi: 10.1038/s41374-018-0093-9. Epub 2018 Jul 5. Lab Invest. 2018. PMID: 29977037 Free PMC article.
The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence.
Wu N, Meng F, Zhou T, Venter J, Giang TK, Kyritsi K, Wu C, Alvaro D, Onori P, Mancinelli R, Gaudio E, Francis H, Alpini G, Glaser S, Franchitto A. Wu N, et al. Among authors: wu c. Am J Pathol. 2018 Oct;188(10):2264-2280. doi: 10.1016/j.ajpath.2018.06.015. Epub 2018 Jul 21. Am J Pathol. 2018. PMID: 30036520 Free PMC article.
Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice.
Luo X, Li H, Ma L, Zhou J, Guo X, Woo SL, Pei Y, Knight LR, Deveau M, Chen Y, Qian X, Xiao X, Li Q, Chen X, Huo Y, McDaniel K, Francis H, Glaser S, Meng F, Alpini G, Wu C. Luo X, et al. Among authors: wu c. Gastroenterology. 2018 Dec;155(6):1971-1984.e4. doi: 10.1053/j.gastro.2018.09.010. Epub 2018 Sep 10. Gastroenterology. 2018. PMID: 30213555 Free PMC article.
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