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Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.
Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LT, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, Dikic I, Brandts C, Iozzo RV, Wygrecka M, Schaefer L. Poluzzi C, et al. Among authors: roedig h. Kidney Int. 2019 Mar;95(3):540-562. doi: 10.1016/j.kint.2018.10.037. Epub 2019 Jan 31. Kidney Int. 2019. PMID: 30712922 Free article.
Biglycan is a new high-affinity ligand for CD14 in macrophages.
Roedig H, Nastase MV, Frey H, Moreth K, Zeng-Brouwers J, Poluzzi C, Hsieh LT, Brandts C, Fulda S, Wygrecka M, Schaefer L. Roedig H, et al. Matrix Biol. 2019 Apr;77:4-22. doi: 10.1016/j.matbio.2018.05.006. Epub 2018 May 17. Matrix Biol. 2019. PMID: 29777767