Zhou P - Search Results

1

Structure-Activity Relationship of Sulfonyl Piperazine LpxH Inhibitors Analyzed by an LpxE-Coupled Malachite Green Assay.

Lee M, Zhao J, Kwak SH, Cho J, Lee M, Gillespie RA, Kwon DY, Lee H, Park HJ, Wu Q, Zhou P, Hong J. Lee M, et al. Among authors: zhou p. ACS Infect Dis. 2019 Apr 12;5(4):641-651. doi: 10.1021/acsinfecdis.8b00364. Epub 2019 Feb 5. ACS Infect Dis. 2019. PMID: 30721024 Free PMC article.

2

Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli.

Barb AW, McClerren AL, Snehelatha K, Reynolds CM, Zhou P, Raetz CR. Barb AW, et al. Among authors: zhou p. Biochemistry. 2007 Mar 27;46(12):3793-802. doi: 10.1021/bi6025165. Epub 2007 Mar 3. Biochemistry. 2007. PMID: 17335290 Free PMC article.

3

Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.

Barb AW, Leavy TM, Robins LI, Guan Z, Six DA, Zhou P, Hangauer MJ, Bertozzi CR, Raetz CR. Barb AW, et al. Among authors: zhou p. Biochemistry. 2009 Apr 14;48(14):3068-77. doi: 10.1021/bi900167q. Biochemistry. 2009. PMID: 19256534 Free PMC article.

4

Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis.

Zeng D, Zhao J, Chung HS, Guan Z, Raetz CR, Zhou P. Zeng D, et al. Among authors: zhou p. J Biol Chem. 2013 Feb 22;288(8):5475-86. doi: 10.1074/jbc.M112.447607. Epub 2013 Jan 11. J Biol Chem. 2013. PMID: 23316051 Free PMC article.

5

The UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis utilizes Mn2+ cluster for catalysis.

Young HE, Donohue MP, Smirnova TI, Smirnov AI, Zhou P. Young HE, et al. Among authors: zhou p. J Biol Chem. 2013 Sep 20;288(38):26987-27001. doi: 10.1074/jbc.M113.497636. Epub 2013 Jul 29. J Biol Chem. 2013. PMID: 23897835 Free PMC article.

6

Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors.

Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Liang X, et al. Among authors: zhou p. J Med Chem. 2013 Sep 12;56(17):6954-6966. doi: 10.1021/jm4007774. Epub 2013 Aug 21. J Med Chem. 2013. PMID: 23914798 Free PMC article.

7

Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis.

Chung BC, Zhao J, Gillespie RA, Kwon DY, Guan Z, Hong J, Zhou P, Lee SY. Chung BC, et al. Among authors: zhou p. Science. 2013 Aug 30;341(6149):1012-1016. doi: 10.1126/science.1236501. Science. 2013. PMID: 23990562 Free PMC article.

8

Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC.

Lee CJ, Liang X, Gopalaswamy R, Najeeb J, Ark ED, Toone EJ, Zhou P. Lee CJ, et al. Among authors: zhou p. ACS Chem Biol. 2014 Jan 17;9(1):237-46. doi: 10.1021/cb400067g. Epub 2013 Oct 31. ACS Chem Biol. 2014. PMID: 24117400 Free PMC article.

9

Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.

Wojtaszek JL, Wang S, Kim H, Wu Q, D'Andrea AD, Zhou P. Wojtaszek JL, et al. Among authors: zhou p. Nucleic Acids Res. 2014 Dec 16;42(22):13997-4005. doi: 10.1093/nar/gku1153. Epub 2014 Nov 20. Nucleic Acids Res. 2014. PMID: 25414354 Free PMC article.

10

Suppression of conformational heterogeneity at a protein-protein interface.

Deis LN, Wu Q, Wang Y, Qi Y, Daniels KG, Zhou P, Oas TG. Deis LN, et al. Among authors: zhou p. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9028-33. doi: 10.1073/pnas.1424724112. Epub 2015 Jul 8. Proc Natl Acad Sci U S A. 2015. PMID: 26157136 Free PMC article.

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